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pitstop 2

inhibits clathrin-independent endocytosis

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Sulfonamides: 2809
    - pitstop 2: 3
- Sulfur Compounds: 278
  - Sulfones: 534
    - Sulfonamides: 2809
      - pitstop 2: 3
  - Thiazoles: 392
    - Thiazolidines: 105
      - pitstop 2: 3

Experts

1.	Haucke, Volker: 2 articles (09/2013 - 01/2013)
2.	Altamura, Louis A: 1 article (09/2013)
3.	Bavari, Sina: 1 article (09/2013)
4.	Garrison, Aura R: 1 article (09/2013)
5.	Kota, Krishna P: 1 article (09/2013)
6.	Kuhn, Jens H: 1 article (09/2013)
7.	Kwilas, Steven A: 1 article (09/2013)
8.	Pegoraro, Gianluca: 1 article (09/2013)
9.	Radoshitzky, Sheli R: 1 article (09/2013)
10.	Ruthel, Gordon: 1 article (09/2013)

Related Diseases

1.	Neoplasms (Cancer) 12/01/2023 - "What's more, the CLTA inhibitor Pitstop 2 alone or in combination with sorafenib attenuated tumor growth in mice implanted with PDXs. " 01/17/2013 - "Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells."
2.	Infections 09/01/2013 - "Here we provide confirmatory evidence for CME entry by showing that CCHFV infection is inhibited in cells treated with Pitstop 2, a drug that specifically and reversibly interferes with the dynamics of clathrin-coated pits. "

Related Drugs and Biologics

1.	Clathrin
2.	Sorafenib (BAY 43-9006)