HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

IST-FS 29

structure in first source

Also Known As:

IST-FS-29; triethyltin(IV)lupinyisulfide hydrochloride

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organometallic Compounds: 64
  - Organotin Compounds: 41
    - Trialkyltin Compounds: 1
      - Triethyltin Compounds
        IST-FS 29: 3

Experts

1.	Alama, Angela: 2 articles (11/2002 - 07/2002)
2.	Barbieri, Federica: 2 articles (11/2002 - 07/2002)
3.	Bruzzo, Cristina: 2 articles (11/2002 - 07/2002)
4.	Schettini, Gennaro: 2 articles (11/2002 - 07/2002)
5.	Sparatore, Fabio: 2 articles (11/2002 - 07/2002)
6.	Bonavia, Rudy: 1 article (11/2002)
7.	Favre, Anna: 1 article (07/2002)
8.	Novelli, Federica: 1 article (07/2002)
9.	Viale, Maurizio: 1 article (07/2002)
10.	Alama, A: 1 article (03/2001)

Related Diseases

1.	Neoplasms (Cancer) 07/01/2002 - "Indeed, repeated administrations of IST-FS 29 resulted in marked significant improvement of antitumor activity against B16F10 (50% of tumor volume inhibition, p = 0.0003) and, to a greater extent, 3LL (90% of tumor volume inhibition, p = 0.0001) tumors. " 07/01/2002 - "These results indicate that IST-FS 29 might be a suitable candidate as an orally administrable anticancer drug and support its further development in human tumor xenografts."
2.	Necrosis 11/01/2002 - "Cell morphology of cultures exposed to IST-FS 29 was assessed by inverted light microscopy after 24 and 72 h and was more consistent with cell death by necrosis which included cell size reduction, vacuolation of cytoplasm, round dying cells. " 03/14/2001 - "In addition, the cytocidal effects exerted by IST-FS 29 appeared more consistent with necrosis or delayed cell death, rather than apoptosis, as shown by morphologic observations under light microscope, DNA fragmentation analysis and flow cytometry. "
3.	Glioblastoma (Glioblastoma Multiforme) 11/01/2002 - "The present experiments were designed to explore the in vitro effects of IST-FS 29 on four human glioblastoma cell lines: A-172, DBTRG.05MG, U-87MG and CAS-1. "
4.	Brain Neoplasms (Brain Tumor) 11/01/2002 - "The present results and our previous data, in vitro and in vivo, indicate the relevant cytotoxic activity of this organo-tin compound and suggest that IST-FS 29 might be a promising novel agent to be developed for the treatment of malignant brain neoplasms."

Related Drugs and Biologics

1.	Tin