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cimigenoside

Also Known As:

beta-D-Xylopyranoside, (3beta,15alpha,16alpha,23R,24S)-16,23-16,24-diepoxy-15,25-dihydroxy-9,19-cyclolanostan-3-yl

Networked: 4 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - cimigenoside: 4

Experts

1.	Dai, Yi: 1 article (03/2021)
2.	He, Liangliang: 1 article (03/2021)
3.	Hu, Liufang: 1 article (03/2021)
4.	Kiyohara, Hiroaki: 1 article (03/2021)
5.	Nagai, Takayuki: 1 article (03/2021)
6.	Song, Xiaojun: 1 article (03/2021)
7.	Yamamoto, Marina: 1 article (03/2021)
8.	Yao, Xinsheng: 1 article (03/2021)
9.	Yao, Zhihong: 1 article (03/2021)
10.	Jia, Hui: 1 article (01/2021)

Related Diseases

1.	Psoriasis (Pustulosis Palmaris et Plantaris) 01/01/2020 - "Natural Compound Mixture, Containing Emodin, Genipin, Chlorogenic Acid, Cimigenoside, and Ginsenoside Rb1, Ameliorates Psoriasis-Like Skin Lesions by Suppressing Inflammation and Proliferation in Keratinocytes." 01/01/2020 - "This study investigated the therapeutic effects of a natural compound mixture (PSM) of these herbal combinations, containing emodin, genipin, chlorogenic acid, cimigenoside, and ginsenoside Rb1, for the treatment of psoriasis and its underlying molecular mechanisms. "
2.	Inflammation (Inflammations) 03/01/2021 - "And immunomodulatory effect of its representative bioavailable component, cimigenoside on Poly(I:C)-induced airway inflammation." 03/01/2021 - "The immunomodulatory activity evaluation of cimigenoside was achieved on poly(I:C)-induced airway inflammation mouse and BEAS-2B cell models from aspects of neutrophil infiltration, lung inflammation by using microscope analysis, quantification of production and expression of inflammatory cytokine and chemokines by using ELISA and quantitative PCR. " 03/01/2021 - "Oral administration of cimigenoside, a representative triterpene glycoside, could prevent neutrophils infiltration in the lung due to suppression of the production of CXCL2 and CXCL10, and the expression of P-selectin, VCAM1 in poly(I:C)-induced airway inflammation model mice. " 01/01/2020 - "Natural Compound Mixture, Containing Emodin, Genipin, Chlorogenic Acid, Cimigenoside, and Ginsenoside Rb1, Ameliorates Psoriasis-Like Skin Lesions by Suppressing Inflammation and Proliferation in Keratinocytes."
3.	Breast Neoplasms (Breast Cancer) 01/01/2021 - "In this article, the antitumor potential of Cimigenoside against breast cancer in vitro and in vivo study. " 01/01/2021 - "Cimigenoside, natural compound isolated and purified from Cimicifuga dahurica (Turcz.) Maxim has been suggested to utilize for breast cancer treatment, however the mechanism of action has not been elucidated yet. " 01/01/2021 - "The results show that Cimigenoside has a significant inhibitory effect towards the proliferation or metastasis of breast cancer cells via suppressing the Notch signaling pathway-mediated mitochondrial apoptosis and EMT (epithelial mesenchymal transition). " 01/01/2021 - "Cimigenoside functions as a novel γ-secretase inhibitor and inhibits the proliferation or metastasis of human breast cancer cells by γ-secretase/Notch axis."
4.	Pneumonia (Pneumonitis) 03/01/2021 - "The immunomodulatory activity evaluation of cimigenoside was achieved on poly(I:C)-induced airway inflammation mouse and BEAS-2B cell models from aspects of neutrophil infiltration, lung inflammation by using microscope analysis, quantification of production and expression of inflammatory cytokine and chemokines by using ELISA and quantitative PCR. " 01/01/2022 - "Through integrating results from network pharmacology, experiments, and the published literature, isoliquiritigenin, Z-ligustilide, atractylenolide I, atractylenolide III, formononetin, ferulic acid, hesperidin, and cimigenoside were presumed as the bioactive components of BZYQT against pulmonary inflammation. "
5.	Neoplasm Metastasis (Metastasis) 01/01/2021 - "The results show that Cimigenoside has a significant inhibitory effect towards the proliferation or metastasis of breast cancer cells via suppressing the Notch signaling pathway-mediated mitochondrial apoptosis and EMT (epithelial mesenchymal transition). " 01/01/2021 - "Cimigenoside functions as a novel γ-secretase inhibitor and inhibits the proliferation or metastasis of human breast cancer cells by γ-secretase/Notch axis."

Related Drugs and Biologics

1.	Emodin (Archin)
2.	Chlorogenic Acid
3.	ginsenoside Rb1
4.	genipin
5.	Therapeutic Uses
6.	Amyloid Precursor Protein Secretases (beta-Secretase)
7.	P-Selectin
8.	Chemokines
9.	Cytokines
10.	Triterpenes

Related Therapies and Procedures

1.	Oral Administration