unicuspid aortic valve

Also Known As:

acommissural UAV; acommissural aortic valve; acommissural unicuspid aortic valve; unicommissural UAV; unicommissural aortic valve; unicommissural unicuspid aortic valve; unicuspid acommissural aortic valve; unicuspid aortic valves; unicuspid unicommissural aortic valve

Networked: 16 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Cardiovascular Diseases: 94258
- Heart Diseases: 26486
  - Heart Valve Diseases: 1907
    - unicuspid aortic valve: 16

Related Diseases

1.	Pathologic Constriction (Stenosis)
2.	Cardiogenic Shock
3.	Unconsciousness (Loss of Consciousness)
4.	Aortic Dissection
5.	Familial Thoracic 1 Aortic Aneurysm

Experts

1.	Schäfers, Hans-Joachim: 3 articles (01/2022 - 10/2020)
2.	Balint, Brittany: 2 articles (01/2022 - 12/2021)
3.	Kollmann, Catherine: 2 articles (01/2022 - 12/2021)
4.	Daisuke, Tachibana: 1 article (03/2023)
5.	Iwata, Shinichi: 1 article (03/2023)
6.	Juri, Takashi: 1 article (03/2023)
7.	Mori, Takashi: 1 article (03/2023)
8.	Nakajima, Asami: 1 article (03/2023)
9.	Takahashi, Yosuke: 1 article (03/2023)
10.	Yamamoto, Akira: 1 article (03/2023)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to unicuspid aortic valve:

1.	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/01/2021 - "The aim of this study was to determine whether turbulence across the unicuspid aortic valve (UAV) contributes to regional differences in endothelial nitric oxide (eNOS) signaling in the ascending aortic wall. "
2.	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 12/01/2021 - "Commentary: Endothelial nitric oxide synthase in unicuspid aortic valve-related aortopathy: Cause or consequence?" 12/01/2021 - "Endothelial nitric oxide synthase alterations are independent of turbulence in the aorta of patients with a unicuspid aortic valve."
3.	Transforming Growth Factor beta (TGF-beta)IBA 01/01/2022 - "SMAD3 contributes to ascending aortic dilatation independent of transforming growth factor-beta in bicuspid and unicuspid aortic valve disease."
4.	SuspensionsIBA 01/18/2021 - "This raphe suspension technique could be used in a patient with a unicuspid aortic valve to reconstruct a functional left lateral commissure concomitant with anterior neocommissure reconstruction using pericardium. "
5.	Polytetrafluoroethylene (Teflon)FDA Link 10/01/2020 - "Mid-term durability of polytetrafluoroethylene patches in unicuspid aortic valve repair."
6.	Glutaral (Glutaraldehyde)IBA 02/01/2021 - "We present the case of a 21-year-old, fit and asymptomatic male, with unicuspid aortic valve with severe stenosis and ascending aorta dilatation, surgically treated with tricuspidization of the aortic valve with glutaraldehyde-treated autologous pericardium and replacement of the ascending aorta with a straight synthetic graft. "

Therapies and Procedures

1.	Transcatheter Aortic Valve Replacement 04/01/2017 - "Transcatheter Aortic Valve Implantation in a Patient with Unicuspid Aortic Valve." 07/01/2017 - "Unicuspid aortic valve (UAV) offers unique challenges to transcatheter aortic valve replacement (TAVR), due to asymmetric expansion and apposition of the prosthesis during implantation. " 01/01/2023 - "Emergency transcatheter aortic valve replacement in a 35-year-old patient with unicuspid aortic valve disease and cardiogenic shock." 04/03/2020 - "Transcatheter aortic valve implantation in unicuspid aortic valve stenosis." 07/01/2017 - "Transcatheter aortic valve replacement in unicuspid aortic valve stenosis."
2.	Bioprosthesis 04/01/2015 - ""Unicuspid" aortic valve bioprosthesis: a complication of surgery for a left hip Morel-Lavallée lesion?" 08/03/2018 - "Successful transcatheter aortic valve replacement using a self-expanding bioprosthesis in a patient with a unicuspid aortic valve associated with severe regurgitation and cardiogenic shock."
3.	Prostheses and Implants (Prosthesis) 07/01/2017 - "Unicuspid aortic valve (UAV) offers unique challenges to transcatheter aortic valve replacement (TAVR), due to asymmetric expansion and apposition of the prosthesis during implantation. "
4.	Therapeutics 09/01/2020 - "This article aims to give an overview on the most recent literature addressing the pathophysiology, the diagnostic tools and appropriate surgical therapy options of unicuspid aortic valve. "
5.	Replantation 03/01/2015 - "Tricuspidization and reimplantation procedure for unicuspid aortic valve with annuloaortic ectasia."