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ACT-462206
an antagonist of both orexin 1 and oxexin 2 receptors; structure in first source
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrrolidines: 115
ACT-462206: 1
Organic Chemicals: 133
Amides: 2428
Sulfonamides: 2809
ACT-462206: 1
Sulfur Compounds: 278
Sulfones: 534
Sulfonamides: 2809
ACT-462206: 1
Experts
1.
Boss, Christoph
: 1 article (08/2020)
Related Diseases
1.
Sleep Initiation and Maintenance Disorders (Insomnia)
08/12/2020 - "
[1] Then the discovery of ACT-462206, a dual orexin receptor antagonist for the treatment of insomnia disorder with a serendipitously short story from the screening hit to the drug [2] followed by the identification of daridorexant, another dual orexin receptor antagonist.
"
Related Drugs and Biologics
1.
Orexin Receptor Antagonists
2.
daridorexant