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2-amino-5-(4-fluorophenyl)pent-4-ynoic acid

a PET agent for imaging tumors; structure in first source

Also Known As:

(18 F)FPhPA; 2-amino-5-(4-(18 F)fluorophenyl)pent-4-ynoic acid

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Cyclic Amino Acids: 3
    - Aromatic Amino Acids: 467
      - 2-amino-5-(4-fluorophenyl)pent-4-ynoic acid: 1

Experts

1.	Hamann, Ingrit: 1 article (09/2014)
2.	Wang, Monica: 1 article (09/2014)
3.	Way, Jenilee D: 1 article (09/2014)
4.	Wuest, Frank: 1 article (09/2014)
5.	Wuest, Melinda: 1 article (09/2014)

Related Diseases

1.	Neoplasms (Cancer) 09/01/2014 - "Small animal PET studies demonstrated similar high tumor uptake of [(18)F]FPhPA in EMT6 tumor-bearing mice compared to [(18)F]FET reaching a maximum standardized uptake value (SUV) of 1.35 after 60 min p.i.. " 09/01/2014 - "L-[(18)F]FPhPA displayed promising properties as a novel amino acid radiotracer for molecular imaging of system ASC and system L amino acid transporters in cancer."
2.	Breast Neoplasms (Breast Cancer) 09/01/2014 - "The radiopharmacological profile of [(18)F]FPhPA was evaluated in comparison with O-(2-[(18)F]fluoroethyl)-L-tyrosine ([(18)F]FET) using the murine breast cancer cell line EMT6 involving cellular uptake studies, radiotracer uptake competitive inhibition experiments and small animal PET imaging. "

Related Drugs and Biologics

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3.	Amino Acid Transport Systems (Amino Acid Transporter)
4.	Amino Acids