eupatorin-5-methyl ether

has antineoplastic activity; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Androutsopoulos, Vasilis P: 2 articles (10/2014 - 05/2011)
2.	Tsatsakis, Aristeidis M: 1 article (10/2014)
3.	Papakyriakou, Athanasios: 1 article (05/2011)
4.	Spandidos, Demetrios A: 1 article (05/2011)
5.	Vourloumis, Dionisios: 1 article (05/2011)

1.	Neoplasms (Cancer) 05/01/2011 - "Eupatorin-5-methyl ether demonstrated a submicromolar IC(50) in the CYP1-expressing cancer cell line MDA-MB 468, while it was considerably inactive in the normal cell line MCF-10A. "
2.	Breast Neoplasms (Breast Cancer) 10/15/2014 - "Benzo[a]pyrene sensitizes MCF7 breast cancer cells to induction of G1 arrest by the natural flavonoid eupatorin-5-methyl ether, via activation of cell signaling proteins and CYP1-mediated metabolism."