Tatsuya Sawamura Selected Research

Inflammation (Inflammations)

1/2023	LOX-1 deficiency increases ruptured abdominal aortic aneurysm via thinning of adventitial collagen.
12/2022	Lectin-like oxidized low-density lipoprotein receptor 1 attenuates pneumonia-induced lung injury.
1/2021	Critical role of oxidized LDL receptor-1 in intravascular thrombosis in a severe influenza mouse model.
4/2018	123I-Labeled oxLDL Is Widely Distributed Throughout the Whole Body in Mice.
1/2018	Smoking cessation reduces the lectin-like low-density lipoprotein receptor index, an independent cardiovascular risk marker of vascular inflammation.
12/2017	Electronegative Low-Density Lipoprotein L5 Induces Adipose Tissue Inflammation Associated With Metabolic Syndrome.
6/2015	Lectin-like oxidized low-density lipoprotein receptor-1 abrogation causes resistance to inflammatory bone destruction in mice, despite promoting osteoclastogenesis in the steady state.
2/2015	High-salt in addition to high-fat diet may enhance inflammation and fibrosis in liver steatosis induced by oxidative stress and dyslipidemia in mice.
1/2013	Lectin-like oxidized low-density lipoprotein receptor-1 plays an important role in vascular inflammation in current smokers.
1/2012	Dietary cholesterol oxidation products accelerate plaque destabilization and rupture associated with monocyte infiltration/activation via the MCP-1-CCR2 pathway in mouse brachiocephalic arteries: therapeutic effects of ezetimibe.

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Tatsuya Sawamura Research Topics

Disease

55	Atherosclerosis 01/2023 - 10/2000
27	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 07/2003
16	Inflammation (Inflammations) 01/2023 - 02/2003
13	Atherosclerotic Plaque (Atheroma) 01/2023 - 03/2002
8	Stroke (Strokes) 01/2021 - 04/2010
8	Hypertension (High Blood Pressure) 01/2016 - 03/2002
7	Pre-Eclampsia (Preeclampsia) 10/2023 - 02/2009
6	Myocardial Infarction 01/2021 - 11/2002
6	Coronary Artery Disease (Coronary Atherosclerosis) 02/2016 - 03/2009
6	Osteoarthritis 04/2012 - 11/2002
6	Myocardial Ischemia (Ischemic Heart Diseases) 10/2011 - 01/2003
5	Ischemia 08/2020 - 12/2002
5	Hypercholesterolemia 01/2016 - 09/2003
4	Vascular Diseases (Vascular Disease) 11/2023 - 08/2002
3	Thrombosis (Thrombus) 01/2021 - 09/2007
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2017 - 08/2011
3	Infarction (Infarctions) 03/2016 - 03/2003
3	Acute Coronary Syndrome 02/2015 - 01/2013
3	Arthritis (Polyarthritis) 04/2012 - 09/2002
3	Hyperplasia 07/2008 - 09/2002
3	Reperfusion Injury 03/2003 - 12/2002
2	Infections 01/2024 - 07/2021
2	Rupture 01/2023 - 01/2012
2	Lung Injury 12/2022 - 07/2011
2	Brain Ischemia (Cerebral Ischemia) 01/2020 - 03/2016
2	Dyslipidemias (Dyslipidemia) 01/2019 - 02/2015
2	Confusion (Bewilderment) 01/2017 - 03/2014
2	Ischemic Stroke 03/2016 - 02/2015
2	Necrosis 09/2015 - 03/2003
2	Fibrosis (Cirrhosis) 02/2015 - 04/2003
2	Hyperlipidemias (Hyperlipidemia) 02/2015 - 03/2002
2	Rheumatoid Arthritis 04/2012 - 11/2004
2	Hypertriglyceridemia 08/2011 - 07/2008
2	Choroidal Neovascularization 08/2009 - 12/2004
1	COVID-19 01/2024
1	Aneurysm (Aneurysms) 01/2023
1	Abdominal Aortic Aneurysm 01/2023
1	Pneumonia (Pneumonitis) 12/2022
1	Vascular System Injuries 12/2022
1	Rheumatic Diseases (Rheumatism) 05/2021
1	Virus Diseases (Viral Diseases) 01/2021

Drug/Important Bio-Agent (IBA)

83	oxidized low density lipoproteinIBA 11/2023 - 10/2000
29	LectinsIBA 01/2021 - 09/2002
22	Class E Scavenger Receptors (Lectin Like Oxidized Low Density Lipoprotein Receptor 1)IBA 10/2023 - 09/2002
14	LipidsIBA 01/2023 - 11/2002
12	LigandsIBA 01/2020 - 07/2002
11	Scavenger Receptors (Scavenger Receptor)IBA 10/2023 - 09/2002
11	LDL Lipoproteins (beta Lipoproteins)IBA 01/2020 - 03/2003
8	CholesterolIBA 01/2020 - 04/2003
8	Oxidized LDL ReceptorsIBA 10/2012 - 09/2002
7	Biomarkers (Surrogate Marker)IBA 01/2020 - 04/2010
6	EnzymesIBA 01/2024 - 10/2008
6	CytokinesIBA 01/2021 - 03/2002
6	C-Reactive ProteinIBA 02/2016 - 03/2010
5	Angiotensin IIIBA 11/2021 - 09/2008
5	LDL Receptors (LDL Receptor)IBA 01/2018 - 08/2003
5	Immunoglobulin G (IgG)IBA 01/2006 - 09/2002
4	HDL LipoproteinsIBA 01/2022 - 01/2019
4	SaltsIBA 01/2020 - 04/2010
4	HDL CholesterolIBA 11/2019 - 04/2010
4	Apolipoproteins B (ApoB)IBA 01/2016 - 10/2008
4	Proteins (Proteins, Gene)FDA Link 01/2011 - 02/2003
3	Messenger RNA (mRNA)IBA 01/2024 - 07/2008
3	Lipoproteins (Lipoprotein)IBA 01/2023 - 10/2008
3	Triglycerides (Triacylglycerol)IBA 01/2016 - 02/2015
3	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2015 - 03/2003
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2003 - 08/2002
2	Oxidoreductases (Dehydrogenase)IBA 10/2023 - 10/2006
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2023 - 10/2012
2	CollagenIBA 01/2023 - 07/2008
2	Adenosine Triphosphate (ATP)IBA 08/2020 - 08/2011
2	low density lipoprotein inhibitorIBA 02/2016 - 01/2013
2	ApolipoproteinsIBA 01/2016 - 07/2008
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2014 - 09/2006
2	N 30IBA 11/2013 - 03/2003
2	Superoxides (Superoxide)IBA 05/2012 - 05/2008
2	Nitric Oxide Synthase (NO Synthase)IBA 05/2012 - 10/2009
2	Matrix Metalloproteinases (MMPs)IBA 01/2012 - 09/2006
2	Apolipoproteins E (ApoE)IBA 01/2012 - 10/2008
2	LDL CholesterolIBA 10/2011 - 04/2010
2	Monoclonal AntibodiesIBA 10/2008 - 01/2003
2	Proteoglycans (Proteoglycan)IBA 08/2006 - 09/2002
2	NF-kappa B (NF-kB)IBA 09/2005 - 08/2002
2	Endothelin-1 (Endothelin 1)IBA 09/2003 - 08/2002
1	NAD (NADH)IBA 01/2024
1	Interleukin-6 (Interleukin 6)IBA 01/2024
1	FibrinIBA 01/2024
1	Superoxide DismutaseIBA 10/2023
1	Phosphotransferases (Kinase)IBA 10/2023
1	acetovanillone (apocynin)IBA 10/2023
1	NADP (NADPH)IBA 10/2023
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 10/2023
1	oil red OIBA 01/2023
1	Aligeron (AS 2)IBA 12/2022
1	GTP-Binding Proteins (G-Protein)IBA 11/2021
1	Receptor for Advanced Glycation End ProductsIBA 11/2021
1	Antiviral Agents (Antivirals)IBA 07/2021
1	Prothrombin (Factor II)IBA 01/2021

Therapy/Procedure

4	Therapeutics 12/2022 - 11/2009
4	Ligation 07/2011 - 12/2002