Abstract | BACKGROUND: METHODS AND RESULTS: CONCLUSIONS:
Antioxidant therapy with vitamins C and E restores endothelial function in hyperlipidemic children. Early detection and treatment of endothelial dysfunction in high-risk children may retard the progression of atherosclerosis.
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Authors | Marguerite M Engler, Mary B Engler, Mary J Malloy, Elisa Y Chiu, Monique C Schloetter, Steven M Paul, Markus Stuehlinger, Ken Y Lin, John P Cooke, Jason D Morrow, Paul M Ridker, Nader Rifai, Elizabeth Miller, Joseph L Witztum, Michele Mietus-Snyder |
Journal | Circulation
(Circulation)
Vol. 108
Issue 9
Pg. 1059-63
(Sep 02 2003)
ISSN: 1524-4539 [Electronic] United States |
PMID | 12912807
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- Antioxidants
- Vitamin E
- Ascorbic Acid
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Topics |
- Adolescent
- Adult
- Antioxidants
(therapeutic use)
- Ascorbic Acid
(therapeutic use)
- Brachial Artery
(physiopathology)
- Child
- Cross-Over Studies
- Double-Blind Method
- Endothelium, Vascular
(physiopathology)
- Female
- Humans
- Hyperlipidemias
(diagnosis, drug therapy, physiopathology)
- Male
- Vasodilation
- Vitamin E
(therapeutic use)
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