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Vitelliform Macular Dystrophy

Autosomal dominant hereditary maculopathy with childhood-onset accumulation of LIPOFUSION in RETINAL PIGMENT EPITHELIUM. Affected individuals develop progressive central acuity loss, and distorted vision (METAMORPHOPSIA). It is associated with mutations in bestrophin, a chloride channel.
Also Known As:
Adult-Onset Vitelliform Macular Dystrophy; Best Disease; Best Macular Dystrophy; Best Vitelliform Macular Dystrophy; Best's Disease; Foveomacular Dystrophy, Adult-Onset; Foveomacular Dystrophy, Adult-Onset, With Choroidal Neovascularization; Juvenile-Onset Vitelliform Macular Dystrophy; Macular Degeneration, Polymorphic Vitelline; Macular Dystrophy, Vitelliform; Macular Dystrophy, Vitelliform, Adult-Onset; Vitelliform Dystrophy; Vitelliform Macular Dystrophy Type 2; Vitelliform Macular Dystrophy, Adult-Onset; Vitelliform Macular Dystrophy, Early-Onset; Vitelliform Macular Dystrophy, Juvenile-Onset; Adult Onset Vitelliform Macular Dystrophy; Adult-Onset Foveomacular Dystrophies; Adult-Onset Foveomacular Dystrophy; Disease, Best; Disease, Best's; Dystrophies, Adult-Onset Foveomacular; Dystrophies, Vitelliform Macular; Dystrophy, Adult-Onset Foveomacular; Dystrophy, Best Macular; Dystrophy, Vitelliform Macular; Foveomacular Dystrophies, Adult-Onset; Foveomacular Dystrophy, Adult Onset; Juvenile Onset Vitelliform Macular Dystrophy; Macular Dystrophies, Vitelliform; Macular Dystrophy, Best; Vitelliform Macular Dystrophies; Vitelliform Macular Dystrophy, Adult Onset; Vitelliform Macular Dystrophy, Early Onset; Vitelliform Macular Dystrophy, Juvenile Onset
Networked: 294 relevant articles (16 outcomes, 16 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Choroidal Neovascularization
2. Bestrophinopathy
3. Angle-Closure Glaucoma (Glaucoma, Angle Closure)
4. Retinal Perforations
5. Pyoderma Gangrenosum

Experts

1. Marmorstein, Alan D: 10 articles (03/2017 - 11/2002)
2. Stone, Edwin M: 9 articles (01/2020 - 02/2003)
3. Marmorstein, Lihua Y: 8 articles (01/2015 - 08/2003)
4. Stanton, J Brett: 7 articles (01/2015 - 11/2002)
5. Weber, Bernhard H F: 6 articles (02/2020 - 04/2002)
6. Hartzell, H Criss: 6 articles (03/2010 - 01/2005)
7. Mullins, Robert F: 5 articles (12/2014 - 11/2005)
8. Yu, Kuai: 5 articles (12/2013 - 11/2006)
9. Peachey, Neal S: 5 articles (03/2010 - 11/2002)
10. Moore, Anthony T: 4 articles (01/2021 - 10/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Vitelliform Macular Dystrophy:
1. Bevacizumab (Avastin)FDA Link
2. Ranibizumab (Lucentis)FDA Link
3. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
4. 1-phenyl-3,3-dimethyltriazene (PDT)IBA
5. acceleratory factor from growth hormone (AcG)IBA
6. Chloride Channels (Chloride Channel)IBA
7. Rhodopsin (Visual Purple)IBA
8. Triamcinolone Acetonide (Azmacort)FDA LinkGeneric
9. Rifampin (Rifampicin)FDA LinkGeneric
10. DapsoneFDA Link

Therapies and Procedures

1. Intravitreal Injections
2. Therapeutics
3. Photochemotherapy (Photodynamic Therapy)
4. Vitrectomy
5. Trabeculectomy (Trabeculoplasty)