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Rifampin (Rifampicin)

A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)
Also Known As:
Rifampicin; Benemycin; Rifadin; Rimactan; Rimactane; Tubocin; Rifamycin, 3-(((4-methyl-1-piperazinyl)imino)methyl)-
Networked: 8826 relevant articles (780 outcomes, 1009 trials/studies)

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Drug Context: Research Results

Experts

1. McIlleron, Helen: 39 articles (05/2022 - 07/2005)
2. Peloquin, Charles A: 34 articles (06/2022 - 09/2002)
3. Menzies, Dick: 31 articles (05/2022 - 08/2004)
4. Maartens, Gary: 30 articles (01/2022 - 02/2008)
5. Denti, Paolo: 28 articles (05/2022 - 09/2011)
6. Diacon, Andreas H: 28 articles (01/2022 - 05/2011)
7. Aarnoutse, Rob E: 26 articles (01/2022 - 10/2006)
8. Meintjes, Graeme: 24 articles (01/2022 - 02/2006)
9. Dooley, Kelly E: 23 articles (10/2022 - 01/2011)
10. Decroo, Tom: 23 articles (04/2022 - 11/2019)

Related Diseases

1. Infections
2. Tuberculosis (Tuberculoses)
3. Pulmonary Tuberculosis
4. Brucellosis (Malta Fever)
5. Pruritus (Itching)

Related Drugs and Biologics

1. Isoniazid (Ftivazide)
2. Ethambutol (Myambutol)
3. Pyrazinamide
4. Anti-Bacterial Agents (Antibiotics)
5. Vancomycin
6. Doxycycline (Periostat)
7. Streptomycin (Streptomycin Sulfate)
8. Minocycline (Cyclops)
9. Ciprofloxacin (Cipro)
10. Clarithromycin (Biaxin)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Catheters
4. Debridement
5. Chemoprevention