Particulate Matter

Particles of any solid substance, generally under 30 microns in size, often noted as PM30. There is special concern with PM1 which can get down to PULMONARY ALVEOLI and induce MACROPHAGE ACTIVATION and PHAGOCYTOSIS leading to FOREIGN BODY REACTION and LUNG DISEASES.

Also Known As:

Air Pollutants, Particulate; Airborne Particulate Matter; Ambient Particulate Matter; Fiber, Ultrafine; Particle, Ultrafine; Particles, Ultrafine; Particulate Air Pollutants; Particulate Matter, Airborne; Particulate Matter, Ambient; Particulate Matter, Ultrafine; Ultrafine Fiber; Ultrafine Fibers; Ultrafine Particle; Ultrafine Particles; Ultrafine Particulate Matter

Networked: 5716 relevant articles (54 outcomes, 1098 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Complex Mixtures: 1947
- Particulate Matter: 5716

Experts

1.	Schwartz, Joel: 70 articles (03/2024 - 02/2002)
2.	Kan, Haidong: 68 articles (05/2024 - 04/2012)
3.	Kaufman, Joel D: 54 articles (04/2024 - 06/2006)
4.	Sun, Qinghua: 52 articles (03/2024 - 12/2005)
5.	Sioutas, Constantinos: 47 articles (02/2024 - 10/2004)
6.	Chen, Renjie: 45 articles (05/2024 - 04/2013)
7.	Martin, Randall V: 43 articles (10/2023 - 09/2012)
8.	van Donkelaar, Aaron: 43 articles (10/2023 - 09/2012)
9.	Rajagopalan, Sanjay: 41 articles (02/2024 - 06/2004)
10.	Laden, Francine: 37 articles (03/2024 - 12/2006)

Related Diseases

1.	Inflammation (Inflammations) 09/16/2020 - "nivalis did not induce airway inflammation and affect particulate matter (PM)-induced inflammatory cells infiltration in lungs but increased phagocytosis with or without PM treatment which might indicate its therapeutic potential for clearance of PM and pathogens in airway." 01/01/2023 - "Respiratory protective effects of Korean Red Ginseng in a mouse model of particulate matter 4-induced airway inflammation." 09/22/2022 - "chinense Miller roots and evaluated its potential protective effects against particulate matter 10 (PM10)-induced inflammation and immune cell death. " 12/01/2021 - "REDD1 (regulated in development and DNA damage-1)/autophagy inhibition ameliorates fine particulate matter (PM2.5) -induced inflammation and apoptosis in BEAS-2B cells." 10/01/2023 - "In this study, we hypothesized that thirdhand Electronic Nicotine Delivery Systems (ENDS) exposures elicit lung and systemic inflammation due to resuspended particulate matter (PM) and inorganic compounds that remain after active vaping has ceased. "
2.	Asthma (Bronchial Asthma) 08/01/2013 - "Several studies highlight the efficacy of portable HEPA purifiers in reduction of indoor particulate matter and improving asthma outcomes. " 01/30/2024 - "Efficacy of Trigonella foenum-graecum Linné in an animal model of particulate matter-induced asthma exacerbation." 04/12/2024 - "The study aimed to reduce personal exposure to fine particulate matter (PM2.5) and improve self-reported asthma-related health. " 04/01/2024 - "Studies have shown that short- and long-term exposure to particulate matter (PM) can increase the risk of asthma morbidity and mortality. " 05/01/2023 - "Ambient particulate matter associates with asthma in high altitude region: A population-based study."
3.	Lung Injury 02/01/2021 - "The research was to explored the protective effects of AS IV against lung injury induced by particulate matter 2.5 (PM2.5) in vivo. " 07/01/2021 - "Aerobic exercise ameliorates particulate matter-induced lung injury in aging rats." 01/01/2022 - "The objective of this study was to observe the protective effect of Rhodiola wallichiana drops in a rat model of fine particulate matter (PM2.5) lung injury. " 01/01/2022 - "Study on Lung Injury Caused by Fine Particulate Matter and Intervention Effect of Rhodiola wallichiana." 10/01/2021 - "Studies revealed that particulate matter 2.5 (PM2.5) enters the lung through the respiratory tract and can damage lung tissue resulting in lung injury primarily via imbalance between pro-inflammatory and anti-inflammatory responses. "
4.	Emphysema 02/01/2015 - "We examined associations of particulate matter (PM2.5, PM10) and nitrogen oxides (NOx) with percent emphysema-like lung on computed tomography (CT). " 07/01/2009 - "We investigated effects of chronic exposure (2 months) to ambient levels of particulate matter (PM) on development of protease-induced emphysema and pulmonary remodeling in mice. " 08/16/2022 - "In addition, toxic particulate matter stimulates epithelial cells to trigger necroptosis, and necroptosis promotes the expulsion of cell contents, the abnormal hyperplasia of pro-inflammatory mediators and the insufficient clearance of dead cells by macrophages; these processes, coupled with the interaction of necroptosis and oxidative stress, collectively result in small-airway disease and emphysema in COPD." 05/01/2024 - "Emphysema, myofibroblast accumulation and airway remodeling can occur in the lungs due to exposure to atmospheric pollution, especially fine particulate matter (PM2.5), leading to chronic obstructive pulmonary disease (COPD). " 12/01/2022 - "Long-term exposure to PM2.5 (particulate matter with an aerodynamic diameter of ≤ 2.5 μm) is associated with pulmonary injury and emphysema in patients with chronic obstructive pulmonary disease (COPD). "
5.	COVID-19 05/30/2023 - "The results of the study showed a significant reduction in the particulate matter (PM) value, which indicates the degree of air pollution, in both the Marmara region and Istanbul during the COVID-19 pandemic. " 09/10/2022 - "Significant reduction of ultrafine particle emission fluxes to the urban atmosphere during the COVID-19 lockdown." 03/15/2024 - "Observational studies have linked exposure to fine (PM2.5) and coarse (PM10) particulate matter air pollution with adverse COVID-19 outcomes, including higher incidence and mortality. " 03/15/2024 - "Causal relationship between particulate matter and COVID-19 risk: A mendelian randomization study." 01/15/2024 - "While numerous studies have explored the potential connection between air pollution, specifically fine particulate matter (PM2.5), and the exacerbation of SARS-CoV-2 infection, the majority of this research has been conducted in foreign regions-Europe, the United States, and China-correlating generalized pollution levels with health-related scopes. "

Related Drugs and Biologics

1.	Air Pollutants (Pollutants, Air)
2.	Particulate Matter
3.	Vehicle Emissions (Emissions, Vehicle)
4.	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)
5.	Taurine
6.	NADH Dehydrogenase
7.	Ozone
8.	Sulfur Dioxide
9.	Carbon Monoxide
10.	Environmental Pollutants (Pollutants, Environmental)

Related Therapies and Procedures

1.	Debridement
2.	Moxibustion
3.	Nebulizers and Vaporizers (Inhaler)
4.	Therapeutics
5.	Ambulatory Care (Outpatient Care)