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Taurine

A conditionally essential nutrient, important during mammalian development. It is present in milk but is isolated mostly from ox bile and strongly conjugates bile acids.

Also Known As:

Taufon; Tauphon; Taurine Hydrochloride; Taurine Zinc Salt (2:1); Taurine, Monopotassium Salt; Ethanesulfonic acid, 2-amino-

Networked: 1730 relevant articles (93 outcomes, 214 trials/studies) for this Drug, Comments

Relationship Network

Drug Context: Research Results

Organic Chemicals: 41
- Hydrocarbons: 351
  - Acyclic Hydrocarbons
    - Alkanes: 48
      - Alkanesulfonic Acids
        Taurine: 1730
        Taurocholic Acid: 730
        taurolidine: 122
        acamprosate: 98
        N-(2-acetamido)-2-aminoethanesulfonic acid: 46
        N-chlorotaurine: 40
        1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea: 37
        2-(N-cyclohexylamino)ethanesulfonic acid: 32
        hypotaurine: 19
        homotaurine: 18
        glutaurin: 10
        taurocyamine: 8
        N-bromotaurine: 6
        acetyltaurine: 3
        OF 4680: 3
        2-aminoethanethiosulfonic acid: 2
        5-aminosalicyltaurine: 1
        bilirubin ditaurine: 1
        chlorohydrate-N-isopropylamide-2-(1-phenylethyl)aminoethanesulfonic acid: 1
        N,N-diacetylhomotaurine: 1
        N,N-dichlorotaurine: 1
        NBD-taurine: 1
        pivaloyltaurine: 1
        taurine N-carbodithioic acid: 1
        taurineamide: 1
        taurocyaminphosphate: 1
        2-(2,3-dihyroxy-9,13-oxy-7-octadecenoylamino)ethanesulfonic acid
        2-aminocyclohexanesulfonic acid
        2-aminocyclopentanesulfonic acid
        2-methyltaurine
        2-phenylisopropyl-2-aminosulfoisopropylamide
        arachidonoyltaurine
        carbamyltaurine
        des(ethanolamine)taurine(16)-gramicidin A
        ditaurobilirubin
        homohypotaurine
        homothiotaurine
        IEM-1702
        lipotaurine
        metaupon
        N,N-dimethylaminomethylene taurine methyl ester
        N-(4-isothiocyano-2-nitrophenyl)-2-aminoethanesulfonate
        N-acetyl-tauryl-proline methylamide
        N-bis(1-carboxyethyl)taurine
        N-isobutyloxycarbonyl-di-n-butylamide-taurine
        N-lauroyl-N-methyltaurine
        N-pentafluorobenzoyl-di-n-butylamide taurine
        NAP taurine
        pantoyltaurine
        phorbasin D
        phorbasin E
        phorbasin F
        S-adenosyl-L-methionine N-ole-1-oyltaurate
        S-adenosylmethionine N-ole-1-oyltaurate
        sodium-N-undec-10-ene-1-oyl taurate
        ST 520
        ST 561
        tauraminopyridine
        taurepar
        tauret
        taurine dichloramine
        taurine-ursodeoxycholate conjugate
        taurinophenetidine
        taurizine
        taurobilirubin
        taurolipid A
        taurolipid B
        taurolipid C
        tauropyrone
        thiotaurine
- Sulfur Compounds: 88
  - Sulfur Acids
    - Sulfonic Acids: 3
      - Alkanesulfonic Acids
        Taurine: 1730
        Taurocholic Acid: 730
        taurolidine: 122
        acamprosate: 98
        N-(2-acetamido)-2-aminoethanesulfonic acid: 46
        N-chlorotaurine: 40
        1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea: 37
        2-(N-cyclohexylamino)ethanesulfonic acid: 32
        hypotaurine: 19
        homotaurine: 18
        glutaurin: 10
        taurocyamine: 8
        N-bromotaurine: 6
        acetyltaurine: 3
        OF 4680: 3
        2-aminoethanethiosulfonic acid: 2
        5-aminosalicyltaurine: 1
        bilirubin ditaurine: 1
        chlorohydrate-N-isopropylamide-2-(1-phenylethyl)aminoethanesulfonic acid: 1
        N,N-diacetylhomotaurine: 1
        N,N-dichlorotaurine: 1
        NBD-taurine: 1
        pivaloyltaurine: 1
        taurine N-carbodithioic acid: 1
        taurineamide: 1
        taurocyaminphosphate: 1
        2-(2,3-dihyroxy-9,13-oxy-7-octadecenoylamino)ethanesulfonic acid
        2-aminocyclohexanesulfonic acid
        2-aminocyclopentanesulfonic acid
        2-methyltaurine
        2-phenylisopropyl-2-aminosulfoisopropylamide
        arachidonoyltaurine
        carbamyltaurine
        des(ethanolamine)taurine(16)-gramicidin A
        ditaurobilirubin
        homohypotaurine
        homothiotaurine
        IEM-1702
        lipotaurine
        metaupon
        N,N-dimethylaminomethylene taurine methyl ester
        N-(4-isothiocyano-2-nitrophenyl)-2-aminoethanesulfonate
        N-acetyl-tauryl-proline methylamide
        N-bis(1-carboxyethyl)taurine
        N-isobutyloxycarbonyl-di-n-butylamide-taurine
        N-lauroyl-N-methyltaurine
        N-pentafluorobenzoyl-di-n-butylamide taurine
        NAP taurine
        pantoyltaurine
        phorbasin D
        phorbasin E
        phorbasin F
        S-adenosyl-L-methionine N-ole-1-oyltaurate
        S-adenosylmethionine N-ole-1-oyltaurate
        sodium-N-undec-10-ene-1-oyl taurate
        ST 520
        ST 561
        tauraminopyridine
        taurepar
        tauret
        taurine dichloramine
        taurine-ursodeoxycholate conjugate
        taurinophenetidine
        taurizine
        taurobilirubin
        taurolipid A
        taurolipid B
        taurolipid C
        tauropyrone
        thiotaurine

Experts

1.	Sil, Parames C: 13 articles (03/2010 - 12/2007)
2.	Manna, Prasenjit: 13 articles (03/2010 - 12/2007)
3.	Azuma, Junichi: 13 articles (01/2009 - 12/2002)
4.	Saransaari, Pirjo: 10 articles (03/2010 - 02/2002)
5.	Oja, Simo S: 10 articles (03/2010 - 02/2002)
6.	Sinha, Mahua: 9 articles (06/2009 - 12/2007)
7.	Schaffer, Stephen W: 9 articles (01/2009 - 05/2002)
8.	Ito, Takashi: 9 articles (01/2009 - 04/2004)
9.	Saransaari, P: 9 articles (01/2008 - 01/2000)
10.	Oja, S S: 9 articles (01/2008 - 01/2000)

Related Diseases

1.	Ischemia 03/12/2010 - "Taurine has been documented to have protective effects on neuronal cells against ischemia in vivo and in vitro. " 01/01/2010 - "Protective effects of taurine against endotoxin-induced acute liver injury after hepatic ischemia reperfusion." 02/01/2004 - "This work shows that the changes in the concentration of myocardial taurine during development correlate with vulnerability to ischemia where low myocardial taurine is associated with improved recovery upon reperfusion." 10/01/1999 - "Double-blind studies to confirm the efficacy of taurine in symptomatic chronic ischemia are needed." 01/01/2008 - "The aim of our study was to explore the effects of taurine on two main pathways of apoptosis induced by ischemia: receptor-mediated and mitochondrial cell death. " Order ALL the reference details at left...
2.	Fibrosis (Cirrhosis) 07/01/2006 - "CONCLUSIONS: Taurine treatment improved the degree of oxidative stress and fibrosis in rat CP. " 03/01/2010 - "CONCLUSION: This study presents novel findings of taurine's role in protecting from TGF-beta1-associated development of lung fibrosis after thoracic radiation." 07/01/2006 - "The aim of this study was to investigate the effects of taurine on oxidative capacity and fibrosis in experimental chronic rat pancreatic fibrosis. " 06/01/2004 - "The aim of this study was to examine taurine concentration in various tissues of a liver damaged with fibrosis (LD) in a rat model before and after exercise. " 03/01/2010 - "Taurine attenuates radiation-induced lung fibrosis in C57/Bl6 fibrosis prone mice." Order ALL the reference details at left...
3.	Cholestasis 01/01/1992 - "Taurine therapy is recommended, because it might be effective for treating neonatal cholestasis." 12/01/1992 - "Although simultaneous addition of UDCA also showed slight improvement, with or without taurine pre-treatment, biliary bile-salt analysis also showed that cholestasis was markedly remitted as the excretion of taurine-conjugated UDCA was increased. " 10/01/2005 - "Taurine and cholestasis associated to TPN. " 05/01/2003 - "The data show that oral supplementation of taurine induces Mrp2 and Bsep expression and may prevent LPS-induced cholestasis." 05/01/2003 - "The effect of oral taurine supplementation on endotoxin-induced cholestasis was investigated in rat liver. " Order ALL the reference details at left...
4.	Seizures (Seizure) 03/01/1993 - "Intraperitoneal taurine alone only reduced the severity of the audiogenic seizures. " 01/01/2003 - "The goal of this study is to examine the potential anti-convulsive effects of the neuro-active amino acid taurine, in the mouse model of KA-induced limbic seizures. " 05/01/2009 - "Thus, a reduction in or total absence of seizures, together with a reduction in or even disappearance of cellular and molecular KA-derived effects, was detected in mice pretreated with taurine compared with those treated only with KA. " 10/15/2008 - "Thus, taurine-fed mice have a functional increase in GAD activity which offers some protection in this seizure model. " 10/15/2008 - "We found that taurine-fed mice have elevated GAD expression and showed a higher threshold for seizure onset when compared with age-matched controls. " Order ALL the reference details at left...
5.	Body Weight (Weight, Body) 01/01/1992 - "Body weight at birth and brain weight at weaning were significantly greater in the very high taurine group than in the normal taurine group, although the greatest growth rate was achieved by the normal taurine group. " 01/01/1998 - "The daily taurine intake of representative Chinese men (18-45 years old, 60 kg body weight, light physical activity) was also studied in 1990 as a part of the Total Diet Study. " 01/01/1996 - "iii. This study showed that the taurine concentration in human milk and the taurine intake of infants were different during lactation between nonvegetarians and lacto-ovovegetarians, and that the intake per kg body weight decreased during lactation. " 02/01/1983 - "Twelve groups of animals were used to study the effect of taurine feeding at a concentration of 0.5% in the drinking water for periods of 1, 3, and 5 days before an iv injection of 18 mumol/100 g body weight of S-LCA. " 11/01/2009 - "Plasma amino acid and whole blood taurine concentrations were not affected by age, BCS, or body weight but were affected by sex and neuter status. " Order ALL the reference details at left...

Related Drugs and Biologics

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3.	Niacin (Nicotinic Acid)
4.	Glutamic Acid (Glutamate)
5.	Calcium
6.	Cholesterol
7.	Bile Acids and Salts (Bile Acids)
8.	Ethanol (Ethyl Alcohol)
9.	beta-Alanine
10.	Insulin (Novolin)

Related Therapies and Procedures

1.	Oral Administration
2.	Intravenous Injections
3.	Total Parenteral Nutrition
4.	Parenteral Nutrition
5.	Electroacupuncture

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