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Narcolepsy

A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with automatic behaviors and AMNESIA. CATAPLEXY; SLEEP PARALYSIS, and hypnagogic HALLUCINATIONS frequently accompany narcolepsy. The pathophysiology of this disorder includes sleep-onset rapid eye movement (REM) sleep, which normally follows stage III or IV sleep. (From Neurology 1998 Feb;50(2 Suppl 1):S2-S7)
Also Known As:
Gelineau's Syndrome; Narcoleptic Syndrome; Gelineau's Syndromes; Gelineaus Syndrome; Narcolepsy Cataplexy Syndrome; Narcolepsy-Cataplexy Syndromes; Narcoleptic Syndromes; Sleep, Paroxysmal; Syndrome, Gelineau; Syndrome, Gelineau's; Syndrome, Narcolepsy-Cataplexy; Syndrome, Narcoleptic; Syndromes, Gelineau's; Syndromes, Narcolepsy-Cataplexy; Syndromes, Narcoleptic; Gelineau Syndrome; Narcolepsy-Cataplexy Syndrome; Paroxysmal Sleep
Networked: 2625 relevant articles (182 outcomes, 406 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Cataplexy
2. Disorders of Excessive Somnolence (Hypersomnia)
3. Sleepiness
4. Obstructive Sleep Apnea
5. Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)

Experts

1. Dauvilliers, Yves: 121 articles (01/2022 - 01/2003)
2. Plazzi, Giuseppe: 110 articles (09/2022 - 08/2003)
3. Mignot, Emmanuel: 110 articles (01/2022 - 02/2000)
4. Pizza, Fabio: 71 articles (09/2022 - 11/2009)
5. Nishino, Seiji: 56 articles (04/2022 - 02/2000)
6. Lammers, Gert Jan: 53 articles (12/2022 - 10/2002)
7. Overeem, Sebastiaan: 42 articles (12/2022 - 10/2002)
8. Lin, Ling: 42 articles (01/2021 - 06/2002)
9. Sakurai, Takeshi: 40 articles (01/2019 - 12/2002)
10. Partinen, Markku: 39 articles (01/2022 - 01/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Narcolepsy:
1. Modafinil (Provigil)FDA Link
2. Sodium Oxybate (gamma Hydroxybutyrate)FDA Link
3. pitolisantIBA
4. solriamfetolIBA
5. Methylphenidate (Ritalin)FDA LinkGeneric
6. OrexinsIBA
7. Antidepressive Agents (Antidepressants)IBA
8. Histamine H3 Receptors (Histamine H3 Receptor)IBA
9. Histamine (Histamine Dihydrochloride)FDA Link
10. Norepinephrine (Noradrenaline)FDA LinkGeneric

Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Immunotherapy
4. Transplantation
5. Aftercare (After-Treatment)