Antidepressive Agents (Antidepressants)

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3535 relevant articles (437 outcomes, 489 trials/studies) found for this Bio-Agent

Description: Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.

Also Known As:

Antidepressants; Antidepressant Drugs; Agents, Antidepressive; Drugs, Antidepressant; Thymoanaleptics; Thymoleptics

Relationship Network

Bio-Agent Context: Research Results

Chemical Actions and Uses

Pharmacologic Actions: 50

Therapeutic Uses: 189

Central Nervous System Agents: 17

Psychotropic Drugs: 1045

Antidepressive Agents: 3535

Tricyclic Antidepressive Agents: 1279

Second-Generation Antidepressive Agents: 7

Experts

1.	Hay, P: 6 articles (01/2006 - 04/2000)
2.	Bacaltchuk, J: 6 articles (01/2006 - 04/2000)
3.	Papakostas, George I: 5 articles (04/2008 - 01/2005)
4.	Kessing, Lars Vedel: 5 articles (01/2008 - 08/2005)
5.	Lima, M S: 5 articles (01/2006 - 04/2000)
6.	Gartlehner, Gerald: 4 articles (10/2008 - 03/2005)
7.	Hansen, Richard A: 4 articles (05/2008 - 03/2005)
8.	Shelton, Richard C: 4 articles (04/2008 - 01/2006)
9.	Andersen, Per Kragh: 4 articles (01/2008 - 01/2007)
10.	Harhoff, Mette: 4 articles (01/2008 - 01/2007)

Related Diseases

1.	Pain (Aches) 06/18/2008 - "This comprehensive approach to pain management should facilitate communication with the patient and help the practitioner select the most appropriate therapeutic strategy, notably the prescription of antidepressants, the efficacy of which we will discuss at the end of the article." 03/15/2008 - "A large body of clinical evidence indicates that antidepressant drugs can also be highly effective against chronic neuropathic pain" 01/01/2006 - "Selection: More than 100 articles that reflected the prevalence of somatic pain in patients with physical illness with and without comorbid depression or anxiety and that evaluated the efficacy of antidepressants in this population were identified and reviewed" 03/01/2004 - "Antidepressants with a dual mechanism of action and combination therapies are associated with higher remission rates, more depression-free days, reduced pain-symptom morbidity, reduced health service utilization, and improved productivity." 01/01/1999 - "Newer antidepressants appear to be safer and better tolerated than older agents for medically ill patients, but do not appear to be as effective for neuropathic pain" Order ALL the reference details at left...
2.	Bipolar Disorder (Mania) 01/01/2008 - "Most of the standard randomized controlled trials report the efficacy of antidepressants in the acute phase of BPD, but the data also indicate higher switch rates to mania and acceleration of mood cycle with their use" 10/01/2001 - "RESULTS: Thirty-five (37%) of the 95 acute treatment phases were associated with a much or very much improved rating in depression on the CGI-BP. Thirteen (14%) of these 95 acute trials of antidepressants as adjuncts to mood stabilizers were associated with switches, seven into hypomania and six into mania" 01/01/2005 - "There are few trials supporting the efficacy of antidepressants in bipolar disorder, and some evidence that they may induce rapid cycling, switching and mania" 02/01/1999 - "Currently available antidepressants may increase the risk of mania and rapid cycling, and mood stabilizers appear to be less effective in treating depression than mania" 03/01/1992 - "Antidepressant drugs are effective in the acute treatment and prevention of depression only, and can even precipitate hypomanic or manic "switches," or "rapid cycling" between mania and depression" Order ALL the reference details at left...
3.	Anxiety Disorders (Anxiety Disorder) 01/01/2006 - "Although currently prescribed antidepressants with actions mediated through alteration of monoaminergic transmission have been proven to be useful for the treatment of depressive and anxiety disorders, they are far from ideal due to their slow onset of action and low rate of responses" 06/01/2004 - "Such an approach recognizes that anxiety, the emotional response to stress, is a key element of depression as well as the defining feature of anxiety disorders, and many antidepressants appear to be effective in the treatment of anxiety disorders as well as depression" 08/01/2001 - "Both the TCA and SSRI antidepressants are effective in treating a wide variety of anxiety disorders" 01/01/2000 - "RESULTS: Both the TCA and SSRI antidepressants are effective in treating a wide variety of anxiety disorders" 09/01/2005 - "While serotonergic antidepressants are now established as first-line pharamcotherapy for generalized social anxiety disorder (SAD), other agents with different mechanisms have shown promise in treating SAD" Order ALL the reference details at left...
4.	Panic Disorder (Panic Attack) 05/01/1986 - "This would be consistent with the fact that most antidepressant drugs are effective in preventing panic attacks" 01/01/2007 - "Antidepressants have been demonstrated to be effective in preventing panic attacks, and in improving anticipatory anxiety and avoidance behaviour" 10/16/2006 - "Antidepressant drugs are effective in the treatment of panic in human panic disorder patients" 03/01/1999 - "Antidepressant drugs are effective in anxiety states, including panic disorder" 05/01/1992 - "Antidepressants seem effective in cases of mixed anxiety-depression or panic disorder" Order ALL the reference details at left...
5.	Depressive Disorder (Melancholia) 08/01/1981 - "Antidepressant drugs have been most specifically beneficial for patients with 'endogenous' depressions, but they should be used whenever this type of depression cannot be definitely ruled out" 11/01/1995 - "In conclusion, the evaluation of risk-benefit ratio associated with antidepressants, drugs of proven efficacy in many indications, should take into account the risks of not treated depressive disorders (chronicity, social functioning and mortality)." 06/01/2007 - "OBJECTIVE: The delayed onset of therapeutic response and the high number of nonresponders to antidepressants remain major clinical problems in depressive disorders" 01/01/2007 - "Firstly, new antidepressant drugs such as SSRIs and SNRIs are very useful to treat depressive disorders without severe adverse effects, which might lead to a good rate of adherance to the drugs" 03/01/2003 - "A significant number of patients with unipolar depression fail to achieve remission after one or a series of antidepressants" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Serotonin (5 Hydroxytryptamine)
2.	Antipsychotic Agents (Antipsychotics)
3.	Anticonvulsants (Antiepileptic Drugs)
4.	Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors)
5.	venlafaxine (Effexor)
6.	Benzodiazepines
7.	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)
8.	Analgesics (Analgesic Drugs)
9.	Lithium
10.	Paroxetine (Paxil)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Therapeutics
3.	Aftercare (After-Treatment)
4.	Analgesia
5.	Autogenic Training

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