Mosquito-Borne Diseases

Infectious diseases transmitted by mosquito vectors. Mosquito-borne human viral diseases include Chikungunya, Dengue, viral encephalitis (e.g., Japanese and St. Louis types), West Nile, Yellow fever, Zika virus infections. Mosquito-borne human parasitic diseases include malaria and lymphatic filariasis. Equine encephalomyelitis and dirofilariasis are mosquito-borne viral diseases mostly in animals.

Also Known As:

Aedes Borne Diseases; Aedes-Borne Disease; Anopheles Borne Diseases; Anopheles-Borne Disease; Disease, Aedes-Borne; Disease, Anopheles-Borne; Disease, Mosquito-Borne Parasitic; Disease, Mosquito-Borne Viral; Mosquito Borne Disease; Mosquito Borne Parasitic Diseases; Mosquito Borne Viral Diseases; Mosquito-Borne Disease; Mosquito-Borne Parasitic Disease; Mosquito-Borne Viral Disease; Parasitic Disease, Mosquito-Borne; Viral Disease, Mosquito-Borne; Aedes-Borne Diseases; Anopheles-Borne Diseases; Mosquito Borne Diseases; Mosquito-Borne Parasitic Diseases; Mosquito-Borne Viral Diseases

Networked: 229 relevant articles (7 outcomes, 18 trials/studies)

Relationship Network

Disease Context: Research Results

Infections: 526564
- Vector Borne Diseases: 374
  - Mosquito-Borne Diseases: 229

Related Diseases

1.	Malaria
2.	Filariasis
3.	Musculoskeletal Pain
4.	Tick-Borne Diseases (Tick-Borne Disease)
5.	Virus Diseases (Viral Diseases)

Experts

1.	Shen, Bo: 4 articles (01/2020 - 01/2014)
2.	Sun, Yan: 4 articles (01/2020 - 01/2014)
3.	Zhou, Dan: 4 articles (01/2020 - 01/2014)
4.	Cheng, Peng: 3 articles (11/2022 - 01/2020)
5.	Gong, Maoqing: 3 articles (11/2022 - 01/2020)
6.	Devine, Gregor J: 3 articles (01/2021 - 07/2009)
7.	Ma, Lei: 3 articles (01/2020 - 01/2014)
8.	Faulde, Michael K: 3 articles (01/2017 - 08/2012)
9.	Webb, Cameron E: 3 articles (12/2016 - 09/2009)
10.	Guo, Xiuxia: 2 articles (11/2022 - 01/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Mosquito-Borne Diseases:

1.	InsecticidesIBA 01/01/2017 - "While insecticide-based vector control strategies are important for the management of mosquito-borne diseases, insecticide-resistance and other logistical hurdles may lower the efficacy of this approach, especially in developing countries. " 01/01/2017 - "Mosquito coil (MC) emits insecticide upon burning which provides limited protection against lethal mosquito borne diseases. " 01/01/2021 - "The aim was to describe cRCT designs which investigated interventions other than non-targeted insecticide for reducing mosquito-borne disease transmission, and comment on the strengths and weaknesses of these study designs. " 01/01/2021 - "Reducing mosquito-borne disease transmission to humans: A systematic review of cluster randomised controlled studies that assess interventions other than non-targeted insecticide." 12/01/2023 - "Controlling mosquito-borne disease is a major global challenge due to the rise of insecticide-resistant mosquitoes. "
2.	VaccinesIBA 09/01/2023 - "While vaccines have been developed, preventing these Aedes-borne diseases continues to primarily depend on monitoring and controlling the vector population. " 01/01/2023 - "Chikungunya, a mosquito-borne viral disease caused by the chikungunya virus (CHIKV), causes a significant global health burden, and there is currently no approved vaccine to prevent chikungunya disease. " 01/01/2023 - "Vaccine development for mosquito-borne viral diseases." 12/06/2022 - "The fight against mosquito-borne diseases requires a combination of new vaccines, non-pharmaceutical interventions and novel strategies to target the mosquito vectors." 09/09/2020 - "Due to the lack of efficient vaccines, the control of mosquito-borne diseases primarily relies on the management of the vector. "
3.	Pyrethrins (Pyrethroids)FDA Link 03/16/2022 - "In anticipation of a country-wide deployment of Pyrethroid-treated nets for control of mosquito-borne diseases in Nigeria, this study assessed susceptibility of Culex quinquefasciatus Say. " 03/16/2022 - "Deployment of pyrethroid-treated nets for control of mosquito-borne diseases in Niger-Delta region of Nigeria is capable of reducing burden of diseases transmitted by Cx. " 03/16/2022 - "Failure of Pyrethroids in control of mosquitoes would impact negatively on the gains recorded in control of mosquito-borne diseases in previous years. " 01/01/2020 - "The wide application of pyrethroids has led to the rapid development of insecticide resistance in mosquitoes, leading to a rise in mosquito-borne diseases. " 01/01/2016 - "If mosquito populations are expanding in space and time because of increased ambient temperatures and cannot be managed as effectively with pyrethroids, the spread of mosquito-borne diseases may pose considerable additional risk to public health."
4.	Salivary Proteins and PeptidesIBA 12/01/2022 - "Immunity to mosquito salivary proteins could provide protection against multiple mosquito-borne diseases and significantly impact public health. " 01/01/2020 - "In animal models, immunity to mosquito salivary proteins protects animals against mosquito-borne disease. "
5.	SmokeIBA 01/01/2020 - "Burning vegetation, leaves, and other plant products have been shown to be effective mosquito repellents for their vector, Aedes spp., but there has been scant research on whether firewood cooking smoke in households influences mosquito populations or mosquito-borne diseases. "
6.	MicroRNAs (MicroRNA)IBA 01/01/2021 - "MicroRNA (miRNA or miR)-based approaches to interrupt the transmission of mosquito-borne diseases have been explored since 2005. A review of these studies and areas in which to proceed is needed. " 10/06/2017 - "This study demonstrates, for the first time, the feasibility of developing a non-defective recombinant MDV micro RNA (miRNA) expression system, and thus providing a powerful tool for the functional analysis of genes in mosquito and establishing a basis for the application of viral paratransgenesis for controlling mosquito-borne diseases. " 01/01/2021 - "Development of miRNA-Based Approaches to Explore the Interruption of Mosquito-Borne Disease Transmission." 01/01/2016 - "So, miRNAs can be used as the molecular target for development of an alternative method for mosquito and mosquito-borne disease control. " 02/20/2020 - "In this review, we summarize the related studies on the innate immune mechanism against mosquito- borne virus infection in mosquitoes about small interfering RNA (siRNA), microRNA (miRNA), and Piwi-interacting RNA (piRNA), aiming to provide a theoretical reference for the prevention and control of mosquito-borne diseases. "
7.	DNA (Deoxyribonucleic Acid)IBA 12/21/2022 - "Many studies of the regulatory DNA and promoters of genes with robust sex-, tissue- and stage-specific expression profiles have supported the development of new tools and strategies that could bring mosquito-borne diseases under control. " 01/01/2021 - "This study supports the use of DNA metabarcoding as a mosquito surveillance tool in Canada which can help identify the emergence of new mosquito-borne disease potential threats." 01/01/2021 - "Mosquito Identification From Bulk Samples Using DNA Metabarcoding: a Protocol to Support Mosquito-Borne Disease Surveillance in Canada." 12/01/2001 - "Here, we show that the polymerase chain reaction (PCR) technique for amplifying and fingerprinting human DNA from mosquito bloodmeals can address this problem for mosquito-borne diseases. " 01/01/2023 - "Although malaria parasites were not found in 126 mosquito pools, meaning more investigation is necessary, the current study adds to the existing DNA barcoding data collection and improves the current understanding of the genetic structure and distribution of anopheline mosquito species, which could be useful for effective control of mosquito-borne diseases."
8.	Biological Control AgentsIBA 06/01/2017 - "This study was conducted to identify native larvicidal biopesticides against Culex pipiens for utilization in the battle against mosquito-borne diseases. " 01/01/2023 - "These results provide strong evidence that dragonflies/damselflies can be effective biological control agents of mosquitoes, and environmental planning to promote them could lower the risk of spreading mosquito-borne diseases in an environmentally friendly and cost-effective manner." 10/27/2021 - "One aspect of mosquito control to curb mosquito-borne diseases has been the use of biological control agents such as fungal entomopathogens. " 01/01/2006 - "MDV have a number of features that make them potentially attractive as biological control agents for mosquito-borne disease. " 08/01/1995 - "The study suggests that this fish could be used, after careful field trial, as a promising and sustainable biological control agent in controlling filariasis and other mosquito-borne diseases."
9.	Proteins (Proteins, Gene)FDA Link 01/01/2011 - "These results provide an understanding of how similarities and disparities among homologous OR proteins relate to olfactory function, which can lead to greater insights into the design of successful strategies for the control of mosquito-borne diseases." 09/01/2010 - "Dengue virus (DENV) is a mosquito-borne disease caused by four genetically and serologically related viruses termed DENV-1, -2, -3 and -4. The DENV envelope (E) protein ectodomain can be divided into three structural domains designated ED1, ED2 and ED3. " 01/01/2022 - "The lethal concentration of purified protein against 3rd instar larvae of Anopheles stephensi had LC50 and LC90 values of 25 μg/ml and 40 μg/ml. It has shown new insight into larvicidal activity and can be used as a new drug against malaria and other mosquito-borne diseases." 11/01/2022 - "Due to the development of insecticide resistance in mosquitoes, with worldwide mosquito-borne diseases resurgence in recent years, recent advances in proteome technology have facilitated a proteome-wide analysis of insecticide resistance-associated proteins in mosquitoes. " 01/04/2021 - "This study presents a novel plasmonic fiber optic sandwich immunobiosensor for the detection of chikungunya, an infectious mosquito-borne disease with chronic musculoskeletal pain and acute febrile illness, by exploiting non-structural protein 3 (CHIKV-nsP3) as a biomarker. "
10.	ProteomeIBA 08/01/2017 - " data of this study are also related to the research article "Mosquito-Borne Diseases and Omics: Salivary gland proteome of the female Aedes aegypti mosquito" (Dhawan et al., 2017) [1]. " 01/01/2017 - "Mosquito-Borne Diseases and Omics: Salivary Gland Proteome of the Female Aedes aegypti Mosquito." 11/01/2022 - "Due to the development of insecticide resistance in mosquitoes, with worldwide mosquito-borne diseases resurgence in recent years, recent advances in proteome technology have facilitated a proteome-wide analysis of insecticide resistance-associated proteins in mosquitoes. "

Therapies and Procedures

1.	Therapeutics 01/01/2021 - "Dengue is the most significant mosquito-borne viral disease; there are no specific therapeutics. " 12/26/2017 - "Dengue virus (DENV) infections cause the most prevalent mosquito-borne viral disease worldwide, for which no therapies are available. " 01/14/2021 - "The recent emergence and re-emergence of mosquito-borne viral diseases (MBVDs) highlight the urgent need for safe and effective vaccines, therapeutics, and vector-control approaches to prevent MBVD outbreaks. " 06/28/2023 - "Due to the limitations of the human therapeutics and vaccines available to treat and prevent mosquito-borne diseases, the primary strategy for disease mitigation is through vector control. " 06/29/2021 - "Since therapeutics or vaccines are lacking for most mosquito-borne diseases, reducing the mosquito vector competence is an effective way to decrease disease burden. "
2.	Chemoprevention 09/01/2022 - "Household clustering supports a novel chemoprophylaxis trial design for a mosquito-borne viral disease." 01/01/2014 - "The simplest, yet most effective, technique for preventing mosquito-borne diseases is the prevention of mosquito bites with repellent, bed nets, and appropriate clothing in addition to chemoprophylaxis. "
3.	Behavior Control 01/01/2023 - "This study suggests that behavioral control may reduce the incidence of new mosquito-borne diseases from endemic areas but may not affect tick-borne disease epidemics within an endemic area."
4.	Insecticide-Treated Bednets 10/01/2013 - "Use of Insecticide-Treated Bednets (ITNs) has been shown to reduce the incidence of mosquito-borne diseases. " 01/01/2016 - "Resistance to pyrethroids is an increasingly important challenge in the control of mosquito-borne diseases, such as malaria or dengue, because one of the main interventions (the distribution of large numbers of long-lasting insecticide-treated bed nets) currently relies entirely on long-lasting pyrethroids. "
5.	Transcutaneous Electric Nerve Stimulation (TENS) 01/01/2017 - "Tens of millions of people live in mosquito-infested regions and controlling mosquito-borne diseases is one of the major interventions aimed at alleviating poverty worldwide. " 10/30/2023 - "Dengue fever (DF) is a mosquito-borne viral disease transmitted by Aedes mosquito species and has been considered a major public health problem in Kassala State for tens of years. "