|1.||McLane, Mary Ann: 3 articles (01/2013 - 01/2005)|
|2.||Tian, Jing: 2 articles (06/2007 - 01/2005)|
|3.||Paquette-Straub, Carrie: 2 articles (06/2007 - 01/2005)|
|4.||Adams, Elizabeth: 1 article (01/2013)|
|5.||Wong, Alice: 1 article (01/2013)|
|6.||Hailey, Stefan: 1 article (01/2013)|
|7.||Penn, Ryan: 1 article (01/2013)|
|8.||Sage, E Helene: 1 article (06/2007)|
|9.||Patel, Vivek: 1 article (06/2007)|
|10.||Funk, Sarah E: 1 article (06/2007)|
|1.||Melanoma (Melanoma, Malignant)
01/01/2013 - "Studies done with melanoma cells on a culture dish and natural killer cells attached to a cantilever tip in atomic force microscopy showed four major populations of interactions which exhibited altered frequency and unbinding strength in the presence of eristostatin."
01/01/2013 - "Direct binding assays using atomic force microscopy showed eristostatin does specifically bind the surface of the six melanoma cell lines tested. "
01/01/2013 - "Cytotoxicity assays suggested that eristostatin makes the melanoma cells a better target for lysis by human natural killer cells. "
01/01/2013 - "Effect of the disintegrin eristostatin on melanoma-natural killer cell interactions."
06/01/2007 - "Eristostatin significantly impaired the migration of five human melanoma cell lines. "
|2.||Wounds and Injuries (Trauma)
06/01/2007 - "In this study, transwell migration and in vitro wound closure assays were used to determine the effect of eristostatin on the migration of melanoma cells. "
06/01/2007 - "Mutations to alanine of seven residues within the RGD loop of eristostatin and four residues outside the RGD loop of eristostatin resulted in significantly less potency in both platelet aggregation and wound closure assays. "
01/01/1995 - "Our study suggests that a major contribution of eristostatin to inhibition of lung colonization is via preferential binding to platelet alpha IIb beta 3 integrin and blocking tumor cells interaction with platelets. "
01/01/1995 - "When injected 1 h after tumor cells, albolabrin, echistatin and barbourin had the same antimetastatic activity, while eristostatin was not active. "
01/01/1995 - "Eristostatin (IC50 7-8 nM) was more potent than echistatin (IC50 74-75 nM), barbourin (IC50 46-60 nM), and albolabrin (IC50 130-165 nM) as an inhibitor of murine platelet aggregation induced by ADP or tumor cells. "
|4.||Neoplasm Metastasis (Metastasis)
05/01/2001 - "Eristostatin, from Eristocophis macmahoni, is a potent inhibitor of ADP-induced platelet aggregation as well as of human and murine melanoma metastases in mouse model systems. "
01/10/1998 - "We investigated the mode of action of the disintegrin eristostatin, an RGD-containing peptide isolated from snake venom, in a human melanoma experimental metastasis model. "
01/10/1998 - "The disintegrin eristostatin interferes with integrin alpha 4 beta 1 function and with experimental metastasis of human melanoma cells."
01/10/1998 - "These findings demonstrate that inhibition of melanoma cell metastasis by RGD-containing peptides such as eristostatin, may be due to interference with alpha 4 beta 1-VCAM binding, in addition to inhibition of the classical RGD-binding integrins."
01/01/1995 - "Four disintegrins, eristostatin, albolabrin, barbourin and echistatin, injected IV into C57BL/6 mice in combination with B16F10 murine melanoma cells, inhibited formation of experimental lung metastases with ID50s of 0.05, 1.0, 0.9, and 3.7 mumoles per mouse, respectively. "
|1.||Integrin beta3 (GPIIIa)
|3.||Snake Venoms (Snake Venom)
|6.||Adenosine Diphosphate (ADP)
|8.||Integrin alpha4beta1 (VLA-4)