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withanolide B

derivative of Withania somnifera

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Dubey, Shreya: 2 articles (03/2021 - 01/2018)
2.	Kallubai, Monika: 2 articles (03/2021 - 01/2018)
3.	Subramanyam, Rajagopal: 2 articles (03/2021 - 01/2018)
4.	Ahmad, Sayeed: 1 article (07/2020)
5.	Basist, Parakh: 1 article (07/2020)
6.	Gaurav,: 1 article (07/2020)
7.	Khan, Washim: 1 article (07/2020)
8.	Parveen, Abida: 1 article (07/2020)
9.	Parveen, Rabea: 1 article (07/2020)
10.	Zahiruddin, Sultan: 1 article (07/2020)

Related Diseases

1.	Rheumatic Diseases (Rheumatism) 01/01/2018 - "Withania somnifera (Ashwagandha) is an efficient medicinal plant known in Ayurveda and Chinese medicine since ancient times, whose extracts are consumed orally as food supplement or as a health tonic owing to its several restorative properties for various CNS disorders, inflammation, tumour, stress, rheumatism etc. In this study, we have analyzed the binding interaction of four derivatives of Withania somnifera (Withanolide A, Withanolide B, Withanoside IV and Withanoside V) with HSA because of their important pharmacological properties. "
2.	Inflammation (Inflammations) 01/01/2018 - "Withania somnifera (Ashwagandha) is an efficient medicinal plant known in Ayurveda and Chinese medicine since ancient times, whose extracts are consumed orally as food supplement or as a health tonic owing to its several restorative properties for various CNS disorders, inflammation, tumour, stress, rheumatism etc. In this study, we have analyzed the binding interaction of four derivatives of Withania somnifera (Withanolide A, Withanolide B, Withanoside IV and Withanoside V) with HSA because of their important pharmacological properties. "
3.	Schizophrenia (Dementia Praecox) 07/15/2020 - "Identified neuroprotective phytoconstituents of Ashwagandha are sitoindosides VII-X, withaferin A, withanosides IV, withanols, withanolide A, withanolide B, anaferine, beta-sitosterol, withanolide D with key pharmacological effects in brain disorders mainly anxiety, Alzheimer's, Parkinson's, Schizophrenia, Huntington's disease, dyslexia, depression, autism, addiction, amyotrophic lateral sclerosis, attention deficit hyperactivity disorder and bipolar disorders. "
4.	Psoriasis (Pustulosis Palmaris et Plantaris) 04/15/2018 - "A simple, highly sensitive ultra-performance liquid chromatography- electrospray ionization-mass spectrometry (LC-ESI-MS) method has been developed to quantify of withanolide B and obakunone (IS) in guinea pig plasma and tissues, and to compare the pharmacokinetics and tissue distribution of withanolide B in normal and psoriasis guinea pigs. "
5.	Huntington Disease (Huntington's Disease) 07/15/2020 - "Identified neuroprotective phytoconstituents of Ashwagandha are sitoindosides VII-X, withaferin A, withanosides IV, withanols, withanolide A, withanolide B, anaferine, beta-sitosterol, withanolide D with key pharmacological effects in brain disorders mainly anxiety, Alzheimer's, Parkinson's, Schizophrenia, Huntington's disease, dyslexia, depression, autism, addiction, amyotrophic lateral sclerosis, attention deficit hyperactivity disorder and bipolar disorders. "

Related Drugs and Biologics

1.	3- rhamnopyranosyl(1- 4)- glucopyranosyl- 12- diacetoxy- 20- hydroxywitha- 5,24- dienolide
2.	withanoside IV
3.	Ashwagandha
4.	withanoside V
5.	Amyloid (Amyloid Fibrils)
6.	gamma-sitosterol (beta-sitosterol)
7.	withanolide D
8.	withaferin A