Intracisternal dimer X: toxicity and prophylaxis.

Abstract

Although Dimer X is said to be a low toxic water soluble contrast medium, epileptic seizures sometimes occur during or after Dimer X ventriculography. The toxicity of this dye was examined in rats and possible prophylactic measures were evaluated. From the results of our experiment it was concluded that Dimer X of low concentration should be used with premedication of Valium and Decadron.

• Authors: M Nishikawa, Y Yonekawa
• Journal: Neuroradiology (Neuroradiology) Vol. 11 Issue 2 Pg. 61-5 (May 31 1976) ISSN: 0028-3940 [Print] Germany
• PMID: 988911 (Publication Type: Journal Article)

Chemical References

• Iothalamic Acid
• Dexamethasone
• Diazepam
• Iothalamate Meglumine

Topics

• Animals
• Cerebral Cortex (physiopathology)
• Dexamethasone (therapeutic use)
• Diazepam (therapeutic use)
• Injections, Spinal
• Iothalamate Meglumine (antagonists & inhibitors)
• Iothalamic Acid (analogs & derivatives)
• Rats
• Seizures (chemically induced, physiopathology, prevention & control)
• Tremor (chemically induced)