[Efficiency of segmental SMANCS/Lip-TAE for hepatocellular carcinoma--comparative studies in the efficacy of segmental SMANCS/Lip-TAI].

Abstract

We compared the segmental SMANCS/Lip-TAI and the segmental SMANCS/Lip-TAE and studied the effectiveness of both treatments and the influence and/or the side effects on liver function. In resected cases, we studied histopathologic examination. The response rate of the group treated by TAI was 28.6%, and that of the group treated by TAE was 76.5%. In the group treated by TAE, the therapeutic effects were good in nodular type HCC, using small doses of SMANCS. In both groups, the incidence and degree of side effects showed no significant difference. Hepatic insufficiency occurred in a few cases of the group treated by TAI. In resected cases, viable areas remained below the tumor capsule. In conclusion, segmental SMANCS/Lip-TAE seemed to be an effective treatment without any serious complications.

• Authors: M Matoba, T Mitsuya, K Ichiyanagi, M Morita, E Kidani, N Ibe, Y Tatsumi, H Tamamura, T Nakagawa, T Okimura, I Yamamoto
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 24 Issue 1 Pg. 37-42 (Jan 1997) ISSN: 0385-0684 [Print] Japan
• PMID: 9020943 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Antineoplastic Agents
• Maleic Anhydrides
• Polystyrenes
• poly(maleic acid-styrene)neocarzinostatin
• Iodized Oil
• Zinostatin

Topics

• Aged
• Antineoplastic Agents (administration & dosage)
• Carcinoma, Hepatocellular (therapy)
• Embolization, Therapeutic
• Female
• Hepatic Artery
• Humans
• Infusions, Intra-Arterial
• Iodized Oil (administration & dosage)
• Liver Neoplasms (therapy)
• Male
• Maleic Anhydrides (administration & dosage)
• Middle Aged
• Polystyrenes (administration & dosage)
• Retrospective Studies
• Zinostatin (administration & dosage, analogs & derivatives)