Improvement of myotonia with carbamazepine in three cases with the Schwartz-Jampel syndrome.

Abstract

Carbamazepine was used as an anti-myotonic agent in three cases with the Schwartz-Jampel syndrome. Clinical myotonia, blepharospasm and a five-stair climbing test improved significantly within two to four months of the initiation of the medication. In the two cases which were followed three and two years, height shifted from under the 3rd centile to the 5th. Carbamazepine may be a drug of choice in the Schwartz-Jampel syndrome.

• Authors: H Topaloğlu, A Serdaroğlu, M Okan, K Gücüyener, M Topçu
• Journal: Neuropediatrics (Neuropediatrics) Vol. 24 Issue 4 Pg. 232-4 (Aug 1993) ISSN: 0174-304X [Print] Germany
• PMID: 8232784 (Publication Type: Case Reports, Journal Article)

Chemical References

• Carbamazepine

Topics

• Blepharospasm (drug therapy)
• Carbamazepine (therapeutic use)
• Child
• Child, Preschool
• Female
• Humans
• Locomotion (drug effects)
• Male
• Myotonia (drug therapy)
• Neurologic Examination (drug effects)
• Osteochondrodysplasias (drug therapy)