[Mechanics of circulation in lowering the blood pressure in different hemodynamic forms of hypertension (author's transl)].

Abstract

The high blood pressure of essential hypertension sustained by an increased peripheral resistance or by cardiac output, or by both of these magnitudes. To examine the mechanics of lowering the blood pressure in these different forms of hypertension on analysis of circulation was carried out on three patients with a cardiac output hypertension and on seven patients with a resistance hypertension before and after lowering the blood pressure by the compound preparation Briserin. The results showed that the influence on the hemodynamics was different. The therapeutic result was due partly to a decrease of the cardiac output and partly to a reduction in vascular peripheral resistance. The increased parameter of circulation decreased during the treatment. Occasionally however the cardiac output as well as the peripheral resistance were decreased or while one of the parameters decreased the other even increased.

• Authors: N Schäfer, B K Härich, B Hansen, M Stauch
• Journal: Medizinische Klinik (Med Klin) Vol. 71 Issue 5 Pg. 205-12 (Jan 30 1976) ISSN: 0025-8458 [Print] Germany
• Vernacular Title: Kreislaufmechanik der Blutdrucksenkung bei hämodynamisch verschiedenen Formen der Hypertonie
• PMID: 814397 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antihypertensive Agents
• Drug Combinations
• Dihydroergotoxine
• Clopamide
• Reserpine

Topics

• Adult
• Aged
• Antihypertensive Agents (therapeutic use)
• Aorta (physiopathology)
• Blood Pressure (drug effects)
• Cardiac Output (drug effects)
• Cardiac Volume (drug effects)
• Clopamide (pharmacology, therapeutic use)
• Dihydroergotoxine (pharmacology, therapeutic use)
• Drug Combinations
• Elasticity
• Exercise Test
• Female
• Hemodynamics (drug effects)
• Humans
• Hypertension (drug therapy, etiology, physiopathology)
• Male
• Middle Aged
• Reserpine (pharmacology, therapeutic use)
• Vascular Resistance (drug effects)