[Indicators of systemic and local immunity in patients with spinal tuberculosis].

Abstract

The examination of 33 patients with tuberculous spondylitis and its sequelae revealed inhibition of T-cell immunity in 40% of the examinees, antituberculous antibodies in the blood of 73% of patients. An enzyme immunoassay detected antituberculous antibodies in cerebrospinal fluid of 70% seropositive sufferers with spinal tuberculosis. Positive results of this test serve a direct indication to spinal decompression and intensive pre- and postoperative antituberculosis treatment.

• Authors: S A Tikhodeev, R I Shenderova, V V Oleĭnik, O A Iakunova
• Journal: Problemy tuberkuleza (Probl Tuberk) Issue 3 Pg. 2-3 ( 1993) ISSN: 0032-9533 [Print] Russia (Federation)
• Vernacular Title: Pokazateli sistemnogo i mestnogo immuniteta u bol'nykh tuberkulezom pozvonochnika.
• PMID: 7984583 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antibodies, Bacterial
• Antitubercular Agents

Topics

• Adult
• Antibodies, Bacterial (cerebrospinal fluid)
• Antitubercular Agents (therapeutic use)
• Female
• Humans
• Immunoenzyme Techniques
• Male
• Middle Aged
• Mycobacterium tuberculosis (immunology)
• Postoperative Care
• Preoperative Care
• T-Lymphocytes (immunology)
• Tuberculosis, Spinal (immunology, surgery)