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Protection of cattle against rinderpest and lumpy skin disease with a recombinant capripoxvirus expressing the fusion protein gene of rinderpest virus.

Abstract
Cattle were protected against challenge with rinderpest and lumpy skin disease viruses by vaccination with a recombinant capripoxvirus containing the fusion protein (F) gene of rinderpest virus. The minimum protective immunising doses for rinderpest and lumpy skin disease were 5.5 x 10(4) plaque forming units (pfu) and 1.5 x 10(3) pfu, respectively.
AuthorsC H Romero, T Barrett, R P Kitching, V M Carn, D N Black
JournalThe Veterinary record (Vet Rec) Vol. 135 Issue 7 Pg. 152-4 (Aug 13 1994) ISSN: 0042-4900 [Print] England
PMID7880246 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Vaccines, Synthetic
  • Viral Fusion Proteins
  • Viral Vaccines
Topics
  • Animals
  • Body Temperature
  • Capripoxvirus (immunology)
  • Cattle
  • Lumpy Skin Disease (prevention & control)
  • Rinderpest (prevention & control)
  • Rinderpest virus (genetics, immunology)
  • Vaccination (veterinary)
  • Vaccines, Synthetic
  • Viral Fusion Proteins (genetics)
  • Viral Vaccines

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