Sodium lactate response and familial risk for panic disorder.

Abstract

OBJECTIVE:

The authors used the family study method to test the hypothesis that sodium lactate response defines two subtypes of panic disorder.

METHOD:

Rates of panic disorder in 142 first-degree relatives of patients who responded to sodium lactate, 88 first-degree relatives of patients who did not respond to sodium lactate, and 231 first-degree relatives of never mentally ill subjects were compared.

RESULTS:

No difference in familial transmission of panic disorder was found between the two patient groups.

CONCLUSIONS:

The findings do not support the notion that panic disorder subtypes are associated with lactate sensitivity.

• Authors: A H Reschke, S Mannuzza, T F Chapman, J D Lipsitz, M R Liebowitz, J M Gorman, D F Klein, A J Fyer
• Journal: The American journal of psychiatry (Am J Psychiatry) Vol. 152 Issue 2 Pg. 277-9 (Feb 1995) ISSN: 0002-953X [Print] United States
• PMID: 7840366 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Biomarkers
• Lactates
• Lactic Acid

Topics

• Biomarkers
• Family
• Female
• Humans
• Lactates
• Lactic Acid
• Male
• Panic Disorder (chemically induced, epidemiology, genetics)
• Risk Factors