Sodium Lactate

01/01/2015 - "Challenge studies in patients with PD reveal that panic attacks may be reliably provoked by agents that lead to acid-base dysbalance such as CO2 inhalation and sodium lactate infusion. "
09/01/2003 - "Beginning with the study of Pitts and McClure, who described the panicogenic activity of sodium lactate, the experimental induction of panic attacks with different challenges has been used to characterize the neurobiology of anxiety. "
03/01/2001 - "In the present study we tested this hypothesis by evaluating the effect of sodium lactate on this aggressiveness, because this substance is recognized to induce spontaneous panic attacks in patients. "
02/01/1995 - "The authors used the family study method to test the hypothesis that sodium lactate response defines two subtypes of panic disorder. "
01/01/1994 - "This study investigated the frequency and severity of symptoms during naturally occurring panic attacks recollected as "usual" and during sodium lactate-induced attacks. "

01/01/2014 - "Infusion of half-molar sodium lactate improved cardiac performance and led to metabolic alkalosis in AHF patients without any detrimental effects on organ function. "
11/01/1986 - "Alkalosis is prominent among the many physiologic and biochemical effects of sodium lactate infusion. "
06/01/1985 - "The metabolic response of the kidney to acute sodium lactate alkalosis."
01/01/2014 - "Further studies are needed to establish the most appropriate dose and indications for sodium lactate infusion in order to prevent the occurrence of severe hypernatremia and metabolic alkalosis."
11/15/1998 - "The 0.5-mol/L sodium lactate infusion induced alkalosis, whereas hypertonic saline and normal saline induced a mild acidosis. "

05/01/1981 - "A conclusion is made that the therapeutic effect of lactasol depends on the amount of the saline injected and on the period of shock during which the saline is injected, as well as on the specific action of sodium lactate."
01/01/2014 - "The results not only suggest unimpaired lactate metabolism during shock in children but document improvement in endothelial barrier function, limited coagulopathy, and avoidance of fluid overload with hypertonic sodium lactate. "
02/01/1998 - "Acid tolerance and acid shock response of Escherichia coli O157:H7 and non-O157:H7 isolates provide cross protection to sodium lactate and sodium chloride."
02/01/1998 - "The survival of Escherichia coli O157:H7 and non-O157:H7 due to an enhanced acid tolerance response (ATR), and enhanced acid shock response (ASR), or the stationary phase protective system when exposed to lactic acid and the resulting cross protection against increased concentration of sodium chloride and sodium lactate was studied. "
03/01/1991 - "After shock, swine were randomly assigned to receive a bolus (4 cc/kg) of either Ringers lactate (RL) or 7.5% hypertonic saline in 6% Dextran 70, followed by either RL or hypertonic sodium lactate to restore mean arterial pressure to baseline. "

09/01/1960 - "[The effect of sodium lactate in acidosic hyperkalemia]."
01/01/1960 - "A comparative analysis of molar sodium lactate and other agents in the treatment of induced hyperkalemia in nephrectomized dogs."
10/01/1957 - "The effects of molar sodium lactate in reversing the cardiotoxic effect of hyperpotassemia."
10/01/1966 - "[The place of molar sodium lactate in the emergency treatment of acute postoperative hyperkalemia]."
11/01/2011 - "This study assessed the safety and efficacy of a potassium cocktail (k-cocktail) containing dextrose, insulin, calcium gluconate, and sodium lactate for treatment of neonatal hyperkalemia. "

08/01/2014 - "Sodium lactate may be a future therapy for treatment and prevention of secondary brain injury. "
08/01/2013 - "We aimed to compare the efficiency of half-molar sodium lactate (SL) versus saline serum solutions in preventing episodes of raised intracranial pressure (ICP) in patients with severe traumatic brain injury (TBI). "
08/02/2011 - "Brain energy depletion in a rodent model of diffuse traumatic brain injury is not prevented with administration of sodium lactate."
03/01/2009 - "Acute infusion of a sodium lactate-based hyperosmolar solution is effective in treating intracranial hypertension following traumatic brain injury. "
01/01/1992 - "The authors compare the results of infusion of a hypotonic fluid (Ringer's lactate, 270 mOsm/liter) to those of a hypertonic fluid (hypertonic sodium lactate, 500 mOsm/liter) in a porcine model of focal cryogenic brain injury. "