Amyloid goitre: CT and MR findings.

Abstract

Two cases of amyloid goitre presented as an enlarged thyroid mass with cystic components. Solid parts of the goitre showed high attenuation on computed tomography (CT) and moderate hypointensity on T1 and T2-weighted images. Fine needle aspiration was negative for amyloid, but pathological studies of surgical specimens demonstrated amyloid infiltration of the thyroid interstitium and regressive colloid cysts. In a patient at risk for systemic amyloidosis, thyroid enlargement with a cystic component suggests amyloid goitre. In this case, needle biopsies should be directed to solid areas of the mass because amyloid material may not be present in the cysts.

• Authors: F J Fontán, F Cordido, J Mosquera, L Valbuena, A Atanes
• Journal: Clinical radiology (Clin Radiol) Vol. 50 Issue 6 Pg. 409-11 (Jun 1995) ISSN: 0009-9260 [Print] England
• PMID: 7789027 (Publication Type: Case Reports, Comparative Study, Journal Article)

Topics

• Adult
• Aged
• Amyloidosis (diagnostic imaging, pathology)
• Cysts (pathology)
• Female
• Goiter (diagnostic imaging, pathology)
• Humans
• Magnetic Resonance Imaging
• Tomography, X-Ray Computed