HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Pharmacokinetic behavior of S-carboxymethylcysteine-Lys in patients with chronic bronchitis.

Abstract
A mass fragmentographic technique was used to study the pharmacokinetic behavior of SCMC-Lys in patients with acute exacerbations of chronic bronchitis and with dense expectoration. Serum and urine levels, as well as bronchial mucus levels and their correlations, were determined. The data suggest that SCMC-Lys diffuses well into bronchial mucus, a useful feature for a mucolytic drug.
AuthorsP C Braga, M Borsa, L De Angelis, R Bossi, L Allegra, F Scaglione, G Scarpazza
JournalClinical therapeutics (Clin Ther) Vol. 4 Issue 6 Pg. 480-8 ( 1982) ISSN: 0149-2918 [Print] United States
PMID7093981 (Publication Type: Journal Article)
Chemical References
  • carbocysteine-lysine
  • Carbocysteine
  • Cysteine
Topics
  • Bronchi (metabolism)
  • Bronchitis (drug therapy)
  • Carbocysteine (analogs & derivatives, metabolism, therapeutic use)
  • Chronic Disease
  • Cysteine (analogs & derivatives)
  • Gas Chromatography-Mass Spectrometry
  • Humans
  • Kinetics
  • Mucus (metabolism)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: