Collagen synthesis in rat gingiva during tooth movement.

Abstract

The response of the gingiva to an increased interdental space was studied by creating a diastema between the central incisors of rats and analyzing autoradiographically the incorporation of H3 proline in the gingiva to detect increased collagen production. In addition, conventional histologic methods were used to determine changes in the gingival architecture. The results indicate that the gingiva responds to an increased space in at least two ways. One is the production of more collagen fibers. The other involves the reorientation of the existing fibers in a horizontal plane as the gingival papilla becomes flattened.

• Authors: M Boisson, A A Gianelly
• Journal: American journal of orthodontics (Am J Orthod) Vol. 80 Issue 3 Pg. 289-99 (Sep 1981) ISSN: 0002-9416 [Print] United States
• PMID: 6945051 (Publication Type: Journal Article)

Chemical References

• Tritium
• Collagen
• Proline

Topics

• Animals
• Autoradiography
• Collagen (biosynthesis)
• Diastema (physiopathology)
• Gingiva (metabolism)
• Male
• Proline (metabolism)
• Rats
• Rats, Inbred Strains
• Tooth Movement Techniques
• Tritium