Needle aspiration cytology of a benign and a malignant schwannoma.

Abstract

The histologic and cytologic features of an uncommon solitary, malignant schwannoma and a benign schwannoma are presented. The benign tumor revealed characteristic interlacing fascicles of spindle-shaped cells on both histology and cytology. The malignant schwannoma produced a variable histologic pattern that was selectively sampled from a recurrence in a scar; only obviously malignant, undifferentiated, spindle-shaped cells not capable of further characterization were seen on cytology. Preliminary experience with immunoperoxidase staining for the neural crest marker S-100 protein has been encouraging and may permit identification of these tumors on aspiration smears.

• Authors: I C Hood, A H Qizilbash, J E Young, S D Archibald
• Journal: Acta cytologica (Acta Cytol) 1984 Mar-Apr Vol. 28 Issue 2 Pg. 157-64 ISSN: 0001-5547 [Print] Switzerland
• PMID: 6583969 (Publication Type: Case Reports, Comparative Study, Journal Article)

Chemical References

• S100 Proteins

Topics

• Aged
• Biopsy, Needle
• Cell Nucleus (pathology)
• Cytoplasm (pathology)
• Female
• Humans
• Male
• Middle Aged
• Nervous System Neoplasms (analysis, pathology)
• Neurilemmoma (analysis, pathology)
• S100 Proteins (analysis)