Antigenic relationships among viruses of the tick-borne encephalitis complex as studied by monoclonal antibodies.

Abstract

Tick-borne encephalitis (TBE) monoclonal antibodies showed haemagglutination-inhibiting (HI) activity against viruses belonging to the TBE complex except of Powassan virus. The HI titre with Kyasanur forest disease virus was lower than with tick-borne encephalitis virus, when monoclonal antibodies were incubated with the antigen at +4 degrees C for 30 min. Langat virus could be distinguished from other viruses of the TBE complex when the antigen was incubated with monoclonal antibodies at +4 degrees C for 18 hr. A close antigenic relationship was demonstrated between tick-borne encephalitis, louping-ill, Negishi and Omsk haemorrhagic fever viruses.

• Authors: M Gresíková, M Sekeyová
• Journal: Acta virologica (Acta Virol) Vol. 28 Issue 1 Pg. 64-8 (Jan 1984) ISSN: 0001-723X [Print] Slovakia
• PMID: 6201061 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Antibodies, Monoclonal
• Epitopes

Topics

• Antibodies, Monoclonal (immunology)
• Encephalitis Viruses, Tick-Borne (immunology)
• Epitopes
• Hemagglutination Inhibition Tests