Azatadine maleate/pseudoephedrine sulfate repetabs versus placebo in the treatment of severe seasonal allergic rhinitis.

Abstract

The symptoms of seasonal allergic rhinitis can be alleviated by the use of an antihistamine and a decongestant. The efficacy and safety of the combination of azatadine maleate and pseudoephedrine sulfate were examined in this double-blind study comparing active drug to placebo. While 74% of the patients administered the combination drug showed marked improvement in the signs and symptoms of seasonal allergic rhinitis, only 29% of patients receiving placebo demonstrated improvement. Adverse reactions were mild and transient.

• Authors: J C Tarasido
• Journal: The Journal of international medical research (J Int Med Res) Vol. 8 Issue 6 Pg. 391-4 ( 1980) ISSN: 0300-0605 [Print] England
• PMID: 6108262 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)

Chemical References

• Drug Combinations
• Histamine H1 Antagonists
• Cyproheptadine
• azatadine
• Ephedrine

Topics

• Adolescent
• Adult
• Cyproheptadine (analogs & derivatives, therapeutic use)
• Double-Blind Method
• Drug Combinations
• Ephedrine (therapeutic use)
• Female
• Histamine H1 Antagonists (therapeutic use)
• Humans
• Male
• Middle Aged
• Rhinitis, Allergic, Seasonal (drug therapy)