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Chlorhexidine as an effective agent against Chlamydia trachomatis in vitro and in vivo.

Abstract
In a small field trial, chlorhexidine (50 micrograms/ml) was as effective against clinical trachoma as topical tetracyclines or oral co-trimoxazole; in vitro, 2.5 micrograms/ml was chlamydicidal.
AuthorsI T Nisbet, D M Graham, P E Spicer, G J Tibbs
JournalAntimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 16 Issue 6 Pg. 855-7 (Dec 1979) ISSN: 0066-4804 [Print] United States
PMID533265 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Placebos
  • Trimethoprim
  • Tetracycline
  • Sulfamethoxazole
  • Chlorhexidine
Topics
  • Child, Preschool
  • Chlamydia trachomatis (drug effects)
  • Chlorhexidine (pharmacology, therapeutic use)
  • HeLa Cells
  • Humans
  • Placebos
  • Sulfamethoxazole (therapeutic use)
  • Tetracycline (therapeutic use)
  • Trachoma (drug therapy)
  • Trimethoprim (therapeutic use)

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