Cystadenolymphoma: an immunohistochemical study with special reference to Ig E and mastcells.

Abstract

Cystadenolymphomas (adenolymphomas) were analysed by immunohistochemical studies for the presence of immunoglobulin A, E, G and M. The distribution pattern was examined by a quantitative analysis. The relative ratio of immunoglobulins was 31.8% (Ig A), 26.6% (Ig E), 28.6% (Ig G) and 13% (Ig M). The different compartments of the lymphoid stroma were analysed separately (subepithelial area, parafollicular area, follicular area). The distribution of mast cells was studied in a parallel approach by the toluidine blue technique. These cells were found in the stroma, but also in the epithelial parts. Our results show that the subepithelial zone in cystadenolymphomas is a region of special cellular reaction (plasma cells, mast cells). The Ig E producing plasma cells and the mastcells seem to play a special role in these tumors.

• Authors: H Yamamoto, J Caselitz, G Seifert
• Journal: Pathology, research and practice (Pathol Res Pract) Vol. 180 Issue 4 Pg. 364-8 (Oct 1985) ISSN: 0344-0338 [Print] Germany
• PMID: 4070069 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Immunoglobulin A
• Immunoglobulin G
• Immunoglobulin M
• Immunoglobulins
• Immunoglobulin E

Topics

• Adenolymphoma (immunology, pathology)
• Humans
• Immunoglobulin A (analysis)
• Immunoglobulin E (analysis)
• Immunoglobulin G (analysis)
• Immunoglobulin M (analysis)
• Immunoglobulins (analysis)
• Mast Cells (cytology, immunology)
• Parotid Gland (immunology)
• Salivary Gland Neoplasms (immunology, pathology)