The aim of this study was to evaluate the efficacy and the safety of liquid monopolar
electrocoagulation in the endoscopic control of major haemorrhage from
peptic ulcers. During the 24-month period of the trial, emergency endoscopy was performed on 480 patients consecutively admitted with acute upper gastrointestinal tract
hemorrhage.
Ulcers were seen in 168 cases (35%). Seventy-eight of these were included in the trial. Active
bleeding was present in 21 cases and stigmata of recent
bleeding were observed in 57. Immediate hemostasis was achieved in nine of 11 patients with active
bleeding ulcers. However, active
bleeding can stop spontaneously (as in four of 10 control patients), which reemphasizes the importance of randomized studies. There was a trend toward
hemostatic benefit for the
electrocoagulation-treated patients with actively
bleeding ulcers. In the group of 31 patients with visible vessels, the
electrocoagulation treatment reduced significantly both the rate of rebleeding and the emergency surgery. In the group of 26 patients with other stigmata of recent
bleeding (fresh or altered clot, or black spots), only in two cases allocated to placebo treatment occurred rebleeding. These patients are at minimal risk of further
bleeding. The results offer support to the contention that liquid monopolar
electrocoagulation is a safe and effective method of reducing the incidence of further
bleeding and emergency surgery. This new technique has the advantages of low cost, easy maintenance, durability, and portability.