Advantages of a Photodiode Detector Endoscopy System in Fluorescence-Guided Percutaneous Liver Biopsies.

Abstract

Image-guided liver biopsies can improve their success rate when combined with the optical detection of Indocyanine Green (ICG) fluorescence accumulated in tumors. Previous works used a camera coupled to a thin borescope to capture and quantify images from fluorescence emission during procedures; however, light-scattering prevented the formation of sharp images, and the time response for weakly fluorescent tumors was very low. Instead, replacing the camera with a photodiode detector shows an improved temporal resolution in a more compact and lighter device. This work presents the new design in a comparative study between both detection technologies, including an assessment of the temporal response and sensitivity to the presence of background fluorescence.

• Authors: Asier Marcos-Vidal, Pedram Heidari, Sheng Xu, Bradford J Wood, Umar Mahmood
• Journal: Optics (Optics (Basel)) Vol. 4 Issue 2 Pg. 340-350 (Jun 2023) ISSN: 2673-3269 [Electronic] Switzerland
• PMID: 38075027 (Publication Type: Journal Article)