Agenesis of the Dorsal Pancreas: Case Report and Review of Age-Related Differences in Presentation.

Abstract

Agenesis of the dorsal pancreas (ADP) is a rare congenital anomaly that occurs when the body and tail of the pancreas fail to develop from the dorsal bud in utero. ADP may be discovered when evaluating conditions arising from the anomaly, such as diabetes mellitus, pancreatitis, and pancreatic insufficiency, but is more commonly found as an incidental finding. To date, fewer than 120 cases have been reported in the literature. We report a 6-year-old male who was found to have ADP on computed tomography during the investigation of abdominal pain and vomiting. We review the variable presentation, genetic mutations, and age-related differences between children and adults with this rare condition.

• Authors: Callie A Grey, Ajinkya Desai, Michael J Nowicki, Natalie Bhesania
• Journal: JPGN reports (JPGN Rep) Vol. 4 Issue 3 Pg. e337 (Aug 2023) ISSN: 2691-171X [Electronic] United States
• PMID: 37600613 (Publication Type: Case Reports)
• Copyright: Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.