This experiment aimed to study the risk factors of
carbapenem-resistant Gram-negative bacteria
pneumonia and death. For this aim, a total of 181 patients with Gram-negative
bacterial pneumonia treated from March 2020 to March 2022 were retrospectively selected and divided into the drug-resistance group (n = 96) and the non-drug resistance group (n = 85) according to the
carbapenem resistance. According to the prognosis, the drug resistance group was divided into the survival group (n = 82) and the non-survival group (n = 14), respectively. The risk factors of single and multi-factor
carbapenem-resistant Gram-negative bacteria
pneumonia and death were studied. Results showed that univariate analysis showed that the rates of recent surgery,
respiratory failure,
shock, indwelling catheterization and disturbance of consciousness were significantly higher in the
drug-resistant group than in the non-
drug-resistant group. The univariate analysis also showed that the rates of
coronary heart disease, diabetes,
shock,
renal insufficiency, deep venous catheterization and
respiratory failure were significantly higher in the non-survival group than in the survival group. Multivariate analysis showed an increased risk of
carbapenem-resistant gram-negative
pneumonia in patients who had used
carbapenem-resistant
antibiotics,
hypertension,
coronary heart disease, and
malignancy in the previous 90 days. Patients with
carbapenem-resistant gram-negative
pneumonia who had
coronary heart disease,
diabetes mellitus,
shock,
renal insufficiency, deep venous catheterization, and
respiratory failure were at increased risk of death. In conclusion, recent surgery,
respiratory failure,
shock, indwelling catheterization, and disturbance of consciousness are risk factors for
carbapenem-resistant Gram-negative bacteria
pneumonia.
Coronary heart disease,
diabetes mellitus,
shock,
renal insufficiency, deep venous catheterization and
respiratory failure are risk factors for death from
carbapenem-resistant gram-negative bacteria
pneumonia.