HLA antigens in ocular cicatricial pemphigoid.

Abstract

HLA antigen frequencies were studied in 45 patients with ocular cicatricial pemphigoid. HLA-B12 was found to have an increased frequency of 44.4% in patients with ocular cicatricial pemphigoid, which was statistically significant when compared with a frequency of 19.6% in the control population (P less than .001 or P less than .031 when corrected for the number of antigens tested). The results of this study suggest that there is an immunogenetic susceptibility to the development of ocular cicatricial pemphigoid.

• Authors: B J Mondino, S I Brown, B S Rabin
• Journal: Archives of ophthalmology (Chicago, Ill. : 1960) (Arch Ophthalmol) Vol. 97 Issue 3 Pg. 479 (Mar 1979) ISSN: 0003-9950 [Print] United States
• PMID: 369492 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• HLA Antigens

Topics

• Eye Diseases (immunology)
• HLA Antigens (analysis)
• Humans
• Skin Diseases, Vesiculobullous (immunology)