Abstract | PURPOSE: METHODS AND MATERIALS: Retrospective analysis of patients with carcinoma of the nasal vestibule who were treated with primary brachytherapy in the Utrecht University Medical Center. RESULTS: In this single center experience over a 17-year period 68 patients with early stage squamous cell carcinoma of the nasal vestibule were treated with brachytherapy. Two patients had lymph node metastases at first clinical presentation. Median follow-up duration was 46.5 months. Five-year locoregional recurrence-free survival, disease-specific survival, and overall survival were 91.1%, 96.1%, and 66.2%, respectively. All recurrences occurred within the first 3 years of follow-up. CONCLUSIONS:
Brachytherapy offers excellent oncological outcomes and is a safe and effective treatment for early stage carcinoma of the nasal vestibule. Recurrences typically occur within 3 years after treatment.
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Authors | W F Julius Scheurleer, Homan Dehnad, W Weibel Braunius, Luuk M Janssen, Bernard M Tijink, Gerben E Breimer, Ernst J Smid, Lot A Devriese, Remco de Bree, Mischa de Ridder, Johannes A Rijken |
Journal | Brachytherapy
(Brachytherapy)
2023 Mar-Apr
Vol. 22
Issue 2
Pg. 221-230
ISSN: 1873-1449 [Electronic] United States |
PMID | 36539317
(Publication Type: Journal Article)
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Copyright | Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved. |
Topics |
- Humans
- Nose Neoplasms
- Follow-Up Studies
- Brachytherapy
(methods)
- Retrospective Studies
- Neoplasm Recurrence, Local
(radiotherapy, etiology)
- Carcinoma, Squamous Cell
(pathology)
- Radiotherapy Dosage
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