State of the Art: Quantitative Cardiac MRI in Cardiac Amyloidosis.

Abstract

Cardiac amyloidosis (CA) is characterized by amyloid infiltration in the myocardial extracellular space, causing heart failure. Patients with CA are currently underdiagnosed. Cardiac involvement is significantly associated with the prognosis and treatment decision-making for CA. Early identification and accurate stratification are the crucial first step in patient management. Comprehensive cardiac MRI-based evaluation of the cardiac structure, function, and myocardial tissue characterization assesses cardiac involvement by tracing disease processes. Emerging quantitative tissue characterization techniques have introduced new measures that can identify early staged CA and monitor disease progression or response after treatment. Quantitative cardiac MRI is becoming an instrumental tool in understanding CA, which leads to changes in individualized patient care. This review aimed to discuss the quantitative cardiac MRI-based assessment of CA using established and emerging techniques. EVIDENCE LEVEL: 5 TECHNICAL EFFICACY: Stage 3.

• Authors: Yubo Guo, Xiao Li, Yining Wang
• Journal: Journal of magnetic resonance imaging : JMRI (J Magn Reson Imaging) Vol. 56 Issue 5 Pg. 1287-1301 (11 2022) ISSN: 1522-2586 [Electronic] United States
• PMID: 35770942 (Publication Type: Journal Article, Review, Research Support, Non-U.S. Gov't)
• Copyright: © 2022 International Society for Magnetic Resonance in Medicine.

Topics

• Amyloidosis (diagnostic imaging)
• Cardiomyopathies (diagnostic imaging)
• Heart (diagnostic imaging)
• Humans
• Magnetic Resonance Imaging
• Myocardium