This study was aimed to explore magnetic resonance imaging (MRI) based on deep learning belief network model in evaluating serum
bile acid profile and adverse perinatal outcomes of
intrahepatic cholestasis of pregnancy (ICP) patients. Fifty ICP pregnant women diagnosed in hospital were selected as the experimental group, 50 healthy pregnant women as the blank group, and 50 patients with
cholelithiasis as the
gallstone group. Deep learning belief network (DLBN) was built by stacking multiple restricted Boltzmann machines, which was compared with the recognition rate of convolutional neural network (CNN) and support vector machine (SVM), to determine the error rate of different recognition methods on the test set. It was found that the error rate of deep learning belief network (7.68%) was substantially lower than that of CNN (21.34%) and SVM (22.41%) (P < 0.05). The levels of
glycoursodeoxycholic acid (GUDCA),
glycochenodeoxycholic acid (GCDCA), and
glycocholic acid (GCA) in the experimental group were dramatically superior to those in the blank group (P < 0.05). Both the experimental group and the blank group had notable clustering of serum
bile acid profile, and the experimental group and the
gallstone group could be better distinguished. In addition, the incidence of amniotic fluid contamination,
asphyxia, and premature perinatal infants in the experimental group was dramatically superior to that in the blank group (P < 0.05). The deep learning confidence model had a low error rate, which can effectively extract the features of liver MRI images. In summary, the serum characteristic
bile acid profiles of ICP were
glycoursodeoxycholic acid,
glycochenodeoxycholic acid, and
glycocholic acid, which had a positive effect on clinical diagnosis. The toxic effects of high concentrations of serum
bile acids were the main cause of adverse perinatal outcomes and
sudden death.