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Interstitial Granulomatous Dermatitis as an Adverse Reaction to Vedolizumab.

Abstract
A 61-year-old woman with a medical history of ulcerative colitis (UC) developed an erythematous, mildly pruritic, maculopapular rash that was histologically consistent with reactive granulomatous dermatitis (RGD) with interstitial granulomatous dermatitis (IGD)-type features 1 week after vedolizumab infusion. Awareness of this complication is key to enhanced recognition and appropriate management as use of this medication becomes more prevalent.
AuthorsKatherine G Beuerlein, Elise D Martin, Lindsay C Strowd
JournalCutis (Cutis) Vol. 109 Issue 3 Pg. 167-169 (Mar 2022) ISSN: 2326-6929 [Electronic] United States
PMID35659138 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antibodies, Monoclonal, Humanized
  • vedolizumab
Topics
  • Antibodies, Monoclonal, Humanized (adverse effects)
  • Autoimmune Diseases
  • Colitis, Ulcerative (drug therapy)
  • Dermatitis (diagnosis, drug therapy, etiology)
  • Female
  • Granuloma (chemically induced, diagnosis)
  • Humans
  • Middle Aged

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