Abstract | BACKGROUND: METHODS: We included 14 studies that compared HXLPE and CPE reporting the incidence of wear-related complications with a minimum follow-up of 10 years. We investigated 5 wear-related complications: osteolysis, excessive wear, linear wear rate, revision surgery due to wear, and progress of osteolysis/aseptic loosening. We conducted a pair-wise meta-analysis to estimate odds ratio (OR) and a proportional meta-analysis to estimate the incidence of each complication. RESULTS: Among 1,175 THAs, 220 osteolysis and 78 wear-related revisions were detected. The use of HXLPE reduced the risk of overall osteolysis (OR 0.30; P = .001), excessive wear (OR 0.10; P < .001), linear wear rate (weighted mean difference 0.09; P < .001), the risk of overall wear-related revisions (OR 0.06; P < .001), and revisions due to aseptic loosening (OR 0.23; P = .015). As per the proportional meta-analysis, the pooled prevalence of osteolysis, excessive wear, and the overall wear-related revision rate were 14%, 8%, and 3% in HXLPE and 25%, 33%, and 20% in CPE, respectively. CONCLUSION:
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Authors | Byung-Ho Yoon, Jung-Wee Park, Young-Kyun Lee, Kyung-Hoi Koo, Chong Bum Chang |
Journal | The Journal of arthroplasty
(J Arthroplasty)
Vol. 37
Issue 11
Pg. 2308-2315.e2
(11 2022)
ISSN: 1532-8406 [Electronic] United States |
PMID | 35568139
(Publication Type: Journal Article, Meta-Analysis, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2022 Elsevier Inc. All rights reserved. |
Chemical References |
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Topics |
- Arthroplasty, Replacement, Hip
(adverse effects)
- Follow-Up Studies
- Hip Prosthesis
(adverse effects)
- Humans
- Osteolysis
(epidemiology, etiology, prevention & control)
- Polyethylene
- Prosthesis Design
- Prosthesis Failure
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