Myocardial Infarction in a 7-Year-Old Girl with Polyarteritis Nodosa.

Abstract

Polyarteritis nodosa (PAN) is a rare systemic vasculitis that affects small to medium-sized arteries. It could affect any organ including the heart. However coronary artery involvements are very rare. We describe a young girl who presented following a histopathological diagnosis of PAN with acute chest pain, high serum troponin, and progressive ischemic changes in the electrocardiogram (ECG). Induction of remission of her disease was done with six-moths Cyclophosphamide infusions and pulse corticosteroids. In addition to anticoagulation and dual antithrombotic therapy, the disease remission was maintained with mycophenolate mofetil which helps in the recovery of coronary disease. Our case illustrates the serious cardiac involvement of PAN in a child that responded to intensive management.

• Authors: Lina Bayazeed, Alaa Felimban, Abdulsalam Alsaiad, Fahd Alsufiani, Jubran Alqanatish
• Journal: Case reports in rheumatology (Case Rep Rheumatol) Vol. 2022 Pg. 2175676 ( 2022) ISSN: 2090-6889 [Print] United States
• PMID: 35516168 (Publication Type: Case Reports)
• Copyright: Copyright © 2022 Lina Bayazeed et al.