Health benefits of spices in individuals with chemotherapeutic drug-induced cardiotoxicity.

Abstract

Cardio-oncology is an emerging field that mainly focuses on a series of cardiovascular diseases caused by chemotherapy and radiotherapy. In the history and culture of human nutrition, spices have been emphasized for their wide range of economic and medical applications in addition to being used as a food-flavoring agent and food preservative. Currently, an increasing number of studies have focused on the health benefits of spices in preventing cardiovascular diseases, particularly their antioxidant effects against cardiovascular damage. This review summarizes the cardioprotective effects of black pepper, cardamom, clove, garlic, ginger, onion, and other spices against chemotherapeutic drug-induced cardiotoxicity and the potential mechanisms. Here, we recommend dietary adjustments with spices for patients with cancer to prevent or mitigate the cardiotoxicity induced by chemotherapeutic agents.

• Authors: Jia Liu, Qing Zhang, Ting Tao, Ling-Yu Wang, Jia-Yi Sun, Chun-Jie Wu, Wen-Jun Zou
• Journal: Current opinion in pharmacology (Curr Opin Pharmacol) Vol. 63 Pg. 102187 (04 2022) ISSN: 1471-4973 [Electronic] England
• PMID: 35245798 (Publication Type: Journal Article, Review)
• Copyright: Copyright © 2022 Elsevier Ltd. All rights reserved.

Chemical References

• Antioxidants

Topics

• Antioxidants (pharmacology, therapeutic use)
• Cardiotoxicity (drug therapy, etiology, prevention & control)
• Cardiovascular Diseases (chemically induced, drug therapy, prevention & control)
• Diet
• Humans
• Spices