Quality of life improvement in breast cancer survivors affected by upper limb lymphedema through a novel multiperspective physical activity methodology: a monocentric pilot study.

Abstract

PURPOSE:

Chronic lymphedema causes psychophysical sequelae jeopardizing quality of life (QoL) of breast cancer (BC) survivors, and lack of effective therapies represents a major challenge for healthcare professionals. Structured adapted physical activity (APA) may represent an effective strategy to attenuate cancer treatment-related impairments and improve QoL. Here, we describe the effects of a specific APA intervention based on a novel multiperspective methodology in counteracting lymphedema-related morphofunctional alterations and improving QoL of BC survivors.

METHODS:

BC survivors with chronic moderate/severe lymphedema attending the Cancer Rehabilitation Center in Florence were assessed before and after 8-week APA. The protocol consisted of both APA specialist-supervised and self-leaded sessions using a tailor-designed proprioceptive board. Body mass index, bioimpedance parameters, indirect upper limb volume measurement, and ultrasonography were performed. Wrist flexion/extension and hand strength functional tests were also executed. QoL, depression/anxiety and pain intensity were evaluated by ULL27, HADS, distress thermometer and NRS questionnaires, respectively.

RESULTS:

Although bioimpedance, ultrasound and volumetric measures remained mostly unchanged, wrist mobility, pain perception, depression, and QoL were all significantly ameliorated after APA.

CONCLUSIONS:

Our findings suggest that a multidisciplinary treatment approach involving APA professionals should be employed in the management of BC-related lymphedema to improve patient psychophysical outcomes and QoL.

• Authors: Giuditta Carretti, Daniela Mirandola, Francesca Maestrini, Lisa Sequi, Sara Germano, Maria Grazia Muraca, Guido Miccinesi, Mirko Manetti, Mirca Marini
• Journal: Breast cancer (Tokyo, Japan) (Breast Cancer) Vol. 29 Issue 3 Pg. 437-449 (May 2022) ISSN: 1880-4233 [Electronic] Japan
• PMID: 35025064 (Publication Type: Journal Article)
• Copyright: © 2021. The Author(s), under exclusive licence to The Japanese Breast Cancer Society.

Topics

• Breast Neoplasms (complications, therapy)
• Cancer Survivors
• Exercise
• Female
• Humans
• Lymphedema (etiology, therapy)
• Pilot Projects
• Quality of Life
• Surveys and Questionnaires
• Survivors
• Upper Extremity