Abstract | BACKGROUND & AIMS: OBJECTIVE: METHODS: Three cohorts were included: AWHS (2318 men), SUN Project (18,266 men and women), and EPIC-Spain (39,393 men and women). Olive oil consumption was measured at baseline using validated questionnaires. RESULTS: In the AWHS, 747 participants had a positive coronary artery calcium score (CACS>0), and the OR (95% CI) was 0.89 (0.72, 1.10) in those with virgin olive oil consumption ≥30 g/day (v. <10 g/day). In the SUN Project (follow-up 10.8 years) 261 total CVD cases occurred, and the HR was 0.57 (0.34, 0.96) for consumptions ≥30 g/day (v. <10 g/day). In the EPIC-Spain (follow-up 22.8 years) 1300 CHD cases and 938 stroke cases occurred; the HRs for stroke according, 0 to <10 (ref), 10 to <20, 20 to <30, and ≥30 g/day of olive oil consumption, were 0.84 (0.70, 1.02), 0.80 (0.66, 0.96), 0.89 (0.74, 1.07). A weaker association was observed for CHD. The association was stronger among those consuming virgin olive oil, instead of common (refined). CONCLUSIONS:
Olive oil is associated with lower risk of CVD and stroke. The maximum benefit could be obtained with a consumption between 20 and 30 g/day. The association could be stronger for virgin olive oil and might operate from the early stages of the disease.
|
Authors | Carolina Donat-Vargas, Helena Sandoval-Insausti, José L Peñalvo, Maria Concepción Moreno Iribas, Pilar Amiano, Maira Bes-Rastrollo, Esther Molina-Montes, Belén Moreno-Franco, Antonio Agudo, Cristina Lasheras Mayo, Martín Laclaustra, Carmen De La Fuente Arrillaga, Maria Dolores Chirlaque Lopez, Maria-José Sánchez, Miguel Angel Martínez-Gonzalez, Guallar-Castillón Pilar |
Journal | Clinical nutrition (Edinburgh, Scotland)
(Clin Nutr)
Vol. 41
Issue 1
Pg. 122-130
(01 2022)
ISSN: 1532-1983 [Electronic] England |
PMID | 34872046
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Copyright | Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved. |
Chemical References |
|
Topics |
- Atherosclerosis
(epidemiology, etiology)
- Cardiovascular Diseases
(epidemiology, etiology)
- Cohort Studies
- Coronary Disease
(epidemiology, etiology)
- Diet
(adverse effects, statistics & numerical data)
- Eating
- Female
- Heart Disease Risk Factors
- Humans
- Male
- Middle Aged
- Olive Oil
(administration & dosage)
- Spain
(epidemiology)
- Stroke
(epidemiology, etiology)
|