Abstract | BACKGROUND: Significant changes in the pathophysiology of older critically ill patients may affect the pharmacokinetics and pharmacodynamics of teicoplanin. This study aimed to determine the optimal teicoplanin blood level in this patient population. METHODS: RESULTS: CONCLUSION: An individualized dosing approach of teicoplanin based on therapeutic drug monitoring is necessary for older critically ill patients.
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Authors | Ling Wang, Mingguang Chen, Hong Ye, Xiaolan Lin, Yixuan Li, Junshan Ruan, Fenghui Lin, Yuxing Lin |
Journal | Current drug metabolism
(Curr Drug Metab)
Vol. 22
Issue 14
Pg. 1124-1131
( 2021)
ISSN: 1875-5453 [Electronic] Netherlands |
PMID | 34809542
(Publication Type: Journal Article)
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Copyright | Copyright© Bentham Science Publishers; For any queries, please email at [email protected]. |
Chemical References |
- Anti-Bacterial Agents
- Teicoplanin
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Topics |
- Aged
- Aged, 80 and over
- Anti-Bacterial Agents
(administration & dosage, pharmacokinetics)
- Critical Illness
- Dose-Response Relationship, Drug
- Drug Monitoring
(methods)
- Female
- Humans
- Male
- Middle Aged
- Precision Medicine
- Teicoplanin
(administration & dosage, pharmacokinetics)
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