Abstract | BACKGROUND: BIOLOGICAL FUNCTIONS: Notably, circular RNAs have a high degree of stability and potential effect on gene regulation. Meanwhile, circular RNAs are involved in the sponge action of microRNAs and mediate protein translation and direct binding, alternative splicing, and histone modification. RELATIONSHIPS WITH CRC: CONCLUSIONS: This article provides a brief review based on the source, structural characteristics, mechanisms, biological functions of circular RNAs, and the relationships between CRC.
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Authors | Shunhao Zhang, Jing Sun, Minqi Gu, Guihua Wang, Xudong Wang |
Journal | Cancer medicine
(Cancer Med)
Vol. 10
Issue 24
Pg. 8725-8740
(12 2021)
ISSN: 2045-7634 [Electronic] United States |
PMID | 34796685
(Publication Type: Journal Article, Review)
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Copyright | © 2021 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. |
Chemical References |
- Biomarkers, Tumor
- RNA, Circular
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Topics |
- Biomarkers, Tumor
(metabolism)
- Colorectal Neoplasms
(diagnosis, pathology, therapy)
- Humans
- RNA, Circular
(therapeutic use)
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